Associate Director, Clinical Science at AVENZO THERAPEUTICS INC

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Full Time

Start Date

Immediate

Expiry Date

21 Jul, 26

Salary

197300.0

Posted On

22 Apr, 26

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Clinical trial design, Clinical data review, Protocol development, Regulatory document authoring, Pharmacovigilance, Data analysis, GCP, ICH guidelines, FDA regulations, EMA regulations, Cross-functional collaboration, Scientific writing, Clinical operations, Oncology, Electronic data capture

Industry

Biotechnology Research

Description

Job Title: Associate Director, Clinical Science Location: Remote U.S. Job Type: Full-Time Who We Are Avenzo Therapeutics, Inc. (“Avenzo” or “Company”) is a clinical-stage biotechnology company focused on developing next-generation oncology therapies for patients. The Company was co-founded in 2022 by Drs. Athena Countouriotis and Mohammad Hirmand (former CEO and CMO of Turning Point Therapeutics, Inc., respectively). With a proven track record in building and scaling biotech companies, our experienced management team is passionate about and committed to building a pipeline of potential best-in-class targeted oncology programs. The Company is headquartered in San Diego, California. Position Summary Reporting to the Executive Director, Clinical Science, the Associate Director, Clinical Science will provide scientific and clinical support for the design conduct, analysis, and reporting of clinical trials. This role contributes hands-on clinical expertise across study teams while collaborating closely across the organization to ensure high-quality scientific execution. Essential Job Functions and Responsibilities * Represent Clinical Sciences on study teams and sub-teams by providing clinical input, addressing relevant and questions, and communicating study progress and emerging data, as needed * Support study oversight with Clinical Operations, ensuring protocol adherence and subject safety * Develop and review site and Clinical Research Associate (CRA) training materials, present at Site Initiation Visits (SIVs) and Investigator Meetings (IV), and support activities of Safety Review and Data Monitoring Committees * Provide clinical input to support the development of trial budgets, CRO scopes of work, and related materials, in collaboration with Clinical Outsourcing and Operations * Collaborate with internal Clinical Operations, Data Management, Biostatistics, Safety, and Regulatory groups to support scientific and operational execution of the clinical protocol * Conduct ongoing clinical data review and support data exploration to identify trends, patterns, and potential safety or efficacy signals * Perform clinical review of trial data for safety and efficacy, assessing consistency and completeness, and provide preliminary interpretations and recommendations to the team * Participate in cross-functional clinical data review meetings and support study closeout activities, including data archiving and contributions to clinical study reports * Contribute to clinical development activities under the guidance from senior Clinical Science or Clinical Development leaders * Review and contribute to the authoring of study protocols, study-related documents, and clinical sections of regulatory documents (e.g., INDs, Investigator’s Brochure [IB], DSURs, regulatory responses, case report forms), ensuring consistency and scientific accuracy * Collaborate with Pharmacovigilance function by supporting clinical review of safety narratives and other safety-related documents and participate in internal safety discussions as needed * Support the Medical Monitor and development team in interactions with study investigators and clinical subject matter experts * Develop and review clinical narrative plans and individual clinical narratives as assigned * Review scientific literature and competitive intelligence to support study and program activities * Develop scientific and clinical presentations for internal and external meetings, and present as needed (e.g., investigator meetings, site visits, and internal review meetings) * Contribute to abstracts, posters, and other scientific meeting materials, including supporting internal review and submission processes as needed * Participate in discussions related to the design and development of early- and late-stage studies, providing clinical science input as needed Preferred Qualifications * Bachelor’s degree required, advanced medical or life sciences or a related area degree preferred (e.g., MS, Ph.D., MPH, PharmD) with 8+ years of experience in the life sciences industry or an equivalent combination of academic and industry experience * Experience conducting clinical data listing reviews and demonstrating familiarity with standard clinical and regulatory references (e.g., CTCAE, MedDRA) * Working knowledge of principles and techniques of clinical data analysis and interpretation * Experience reviewing and contributing to clinical study protocols and related documents * Knowledge of GCP (Good Clinical Practice), ICH, FDA, EMA, and other relevant guidelines and regulations * Proven ability to collaborate within cross-functional teams * Ability to understand and assimilate complex scientific and clinical information. * Demonstrates initiative, strong organizational skills, and attention to detail * Proficiency in Microsoft Word, Excel, PowerPoint, and Electronic Data Capture systems (e.g., RAVE), J-Review, or similar data review tools * Excellent communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholders * Strong analytical and problem-solving abilities, with a strategic mindset * This position requires periodic/regular travel, including up to 20%, which may include overnight travel Physical Demands and Work Environment Physical Demands: * Constant or continuous use of a computer keyboard, monitor, and mouse to perform a variety of tasks * Constant or frequent sitting, standing, or walking * May lift and/or move objects of various weights Work Environment: * Remote: Home office; expected to travel to and work from the Company’s headquarters in San Diego from time to time * Noise level in the work environment is usually moderate * Fast-paced, time sensitive environment with frequently changing priorities * Handle multiple projects simultaneously Reasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position. Salary Range The salary range for this position is $189,300 to $197,300 per year. The final pay offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and years of experience within the job and the industry, education, and skills and certifications. Benefits Provided they meet all eligibility requirements under the applicable plan documents, employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical, dental, vision, and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance, flexible spending accounts, health savings accounts, and voluntary insurance programs, including voluntary life, AD&D accident, and critical illness. Employees will also be able to enroll in the Company’s 401(k) plan. In addition, employees will accrue 10 hours of paid vacation time every month and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year, including a winter closure, subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies, which may be amended from time to time. Other Compensation The hired candidate will be eligible to receive an annual discretionary bonus and an equity award, subject to the terms of the applicable employment agreement, plan documents, and Company policies. The information above is intended to provide a general description of benefits and other compensation and is not a substitute for applicable plan documents or company policies. Applications for this position are anticipated to close on April 23, 2026. For more information about this posting, please contact careers@avenzotx.com [careers@avenzotx.com]. Equal Employment Opportunity Avenzo is committed to providing equal employment opportunities to all employees and applicants without regard to an individual’s actual or perceived protected characteristic or characteristics, or any combination of protected characteristics including race (including traits associated with race, such as hair texture and protective hairstyles, including braids, locks, and twists), ethnicity, religion, religious creed (including religious dress and grooming practices), color, sex (including childbirth, breast feeding, and related medical conditions), gender, gender identity or expression, sexual orientation, national origin, ancestry, citizenship status, uniformed service member and veteran status, marital status, pregnancy, age (40 and over), protected medical condition (including cancer and genetic conditions), genetic information, disability (mental and physical), reproductive health decision-making, medical leave or other types of protected leave (requesting or approved for leave under the Family and Medical Leave Act or the California Family Rights Act), the employee or their family member’s status as a victim of a qualifying act of violence, political activity or affiliation, use of cannabis off the job and away from the workplace, association with an individual who has, or is perceived to have, a protected characteristic or characteristics, or any combination of protected characteristics, or any other protected status in accordance with all applicable federal, state, and local laws. Notice to Search Firms/Third Party Agencies Avenzo does not accept unsolicited resumes from recruiters, employment agencies or search firms without a valid, executed search agreement in place.

Responsibilities

The Associate Director provides scientific and clinical support for the design, conduct, analysis, and reporting of oncology clinical trials. They collaborate with cross-functional teams to ensure protocol adherence, data quality, and regulatory compliance.