Advisor - Scientific Lead, Cell Line Generation at Lilly
Louisville, CO 80027, USA -
Full Time


Start Date

Immediate

Expiry Date

16 Nov, 25

Salary

217800.0

Posted On

16 Aug, 25

Experience

5 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Cell Lines, Pre Clinical Studies, Characterization, Oncology, Primary Cells, Group Meetings, Timelines, Disabilities, Molecular Biology, Cell Biology, Biology, Flow Cytometry

Industry

Information Technology/IT

Description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

POSITION SUMMARY:

We are looking for a highly capable and motivated laboratory-based scientist experienced in cell line generation and characterization. This individual will be a part of the cell line engineering/cell biology team that generates engineered cell lines for our preclinical programs in oncology. The primary responsibilities will include engineering cell lines for use in in vitro mechanistic assays and studies. The right candidate is expected to work within a collaborative team environment, while being able to work independently to design, execute, and optimize experiments. Beyond performing experiments, the scientist will analyze the data from experiments, present the data in meetings and work with the rest of the team to determine the next steps. Position level will be commensurate with applicant’s experience.

  • Roles and Responsibilities of the Position:
  • Engineer various cell lines for pre-clinical studies such as over-expression, genome-editing, reporter lines etc.
  • Maintain cultures of frequently used suspension and adherent cell lines.
  • Deposit and archive cell lines in the company’s repository cell line bank.
  • Keep detailed and accurate laboratory records, present results at group meetings and project team meetings.
  • Viral construct cloning, viral titer measurement, and viral stock maintenance.
  • Perform routine molecular and cell biology techniques like, transfection/electroporation, DNA/RNA/protein extraction, qPCR analysis, western blot analysis, flow cytometry, fluorescent microscopy and so on.

BASIC REQUIREMENTS:

  • PhD in biology, cell biology, molecular biology or a related field and 0-5 years experiences; or MS in biology, cell biology, molecular biology or a related field and 5-8 years experiences
  • Prior cell culture experience with immortalized cell lines, cancer cell lines and/or primary cells
  • Must be organized and efficient and able to work according to timelines.
Responsibilities

We are looking for a highly capable and motivated laboratory-based scientist experienced in cell line generation and characterization. This individual will be a part of the cell line engineering/cell biology team that generates engineered cell lines for our preclinical programs in oncology. The primary responsibilities will include engineering cell lines for use in in vitro mechanistic assays and studies. The right candidate is expected to work within a collaborative team environment, while being able to work independently to design, execute, and optimize experiments. Beyond performing experiments, the scientist will analyze the data from experiments, present the data in meetings and work with the rest of the team to determine the next steps. Position level will be commensurate with applicant’s experience.

  • Roles and Responsibilities of the Position:
  • Engineer various cell lines for pre-clinical studies such as over-expression, genome-editing, reporter lines etc.
  • Maintain cultures of frequently used suspension and adherent cell lines.
  • Deposit and archive cell lines in the company’s repository cell line bank.
  • Keep detailed and accurate laboratory records, present results at group meetings and project team meetings.
  • Viral construct cloning, viral titer measurement, and viral stock maintenance.
  • Perform routine molecular and cell biology techniques like, transfection/electroporation, DNA/RNA/protein extraction, qPCR analysis, western blot analysis, flow cytometry, fluorescent microscopy and so on

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.

  • To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions
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