Application Scientist-Shared Resource Center at St Jude Childrens Research Hospital
Memphis, TN 38105, USA -
Full Time


Start Date

Immediate

Expiry Date

04 Dec, 25

Salary

86320.0

Posted On

04 Sep, 25

Experience

3 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Soft Skills, Maintenance, Cell Biology, Functional Genomics, Immunostaining, Flow Cytometry, Transcriptomics, Imaging Technologies, Leadership, Project Coordination, Molecular Biology, Training, Presentation Skills

Industry

Information Technology/IT

Description

The Application Scientist of the Shared Resource Center will execute processes within highly technical or complex field/ technology to answer novel biological questions (including analysis and reporting of results to end-users; resolution of complex queries from lab mates/ end-users).

Key Responsibilities:

  • Lead the iPSC service line within CytoStem, including reprogramming, differentiation, and characterization workflows.
  • Design, validate, and refine protocols for iPSC reprogramming and lineage-specific differentiation using defined, reproducible systems.
  • Implement advanced QC measures to ensure consistency, pluripotency, genomic integrity, and differentiation potential.
  • Collaborate on the development of analytical pipelines for complex phenotypic and transcriptomic data.
  • Partner with automation engineers, image analysis teams, and bioinformatics collaborators to streamline workflows from reprogramming through functional readout.
  • Support the operation of a stem cell biorepository, including inventory management and distribution strategies.
  • Present findings to internal stakeholders and contribute to high-impact publications and grant applications.
  • Mentor junior staff and help build a team culture focused on innovation, scientific rigor, and service excellence.
  • Educate peers on concepts and processes surrounding cellular reprogramming and differentiation.

Experience:

  • Ph.D. in Cell Biology, Stem Cell Biology, Molecular Biology, or related field strongly preferred.
  • Extensive hands-on experience with human iPSC culture, reprogramming, and lineage-specific differentiation.
  • Proven success in developing and scaling stem cell protocols in an academic or biotech environment.
  • Experience in functional genomics and live-cell imaging technologies is strongly preferred.
  • Experience in characterization techniques including qPCR, flow cytometry, immunostaining, microscopy, and transcriptomics is preferred.

Leadership & Soft Skills:

  • Experience mentoring junior scientists.
  • Exceptional organizational, communication, and presentation skills.
  • Ability to work independently and collaboratively in a fast-paced research environment.

MINIMUM EDUCATION AND/OR TRAINING:

  • Bachelor’s degree in a relevant scientific area

MINIMUM EXPERIENCE:

  • 8 + years of research experience is required.
  • 6 + years of research experience is required with a Master’s degree.
  • 3 + years of research experience is required with a PHD.
  • Prior experience in relevant lab techniques preferred.
  • Experience in lab and scientific project coordination, maintenance, and other research support activities preferred.
  • Demonstrated understanding of the field and related trends.
Responsibilities
  • Lead the iPSC service line within CytoStem, including reprogramming, differentiation, and characterization workflows.
  • Design, validate, and refine protocols for iPSC reprogramming and lineage-specific differentiation using defined, reproducible systems.
  • Implement advanced QC measures to ensure consistency, pluripotency, genomic integrity, and differentiation potential.
  • Collaborate on the development of analytical pipelines for complex phenotypic and transcriptomic data.
  • Partner with automation engineers, image analysis teams, and bioinformatics collaborators to streamline workflows from reprogramming through functional readout.
  • Support the operation of a stem cell biorepository, including inventory management and distribution strategies.
  • Present findings to internal stakeholders and contribute to high-impact publications and grant applications.
  • Mentor junior staff and help build a team culture focused on innovation, scientific rigor, and service excellence.
  • Educate peers on concepts and processes surrounding cellular reprogramming and differentiation
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