Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
The Associate Bioprocess Technician’s responsibilities span from Media and Buffer Preparation and introduction to Cell Culture and Purification processes.

Key Accountabilities/Core Job Responsibilities:

• Responsibilities span across media and buffer preparations for production campaigns. This includes, but is not limited to, media and buffer preparation, set-up and take-down of equipment and single-use assemblies, and both testing and actual operations.
• Introduction to unit operations as requested which include but not limited to cell culture and purification processes.
• Document all manufacturing activities accurately and comprehensively in batch records and document all non-conformance issues
• Conduct all activities in accordance with company policies & Standard Operating Procedures, global regulatory guidelines, environmental guidelines, as appropriate, etc.
• Remain up to date on all assigned training and ensure completion of any training required for GMP activities prior to executing those activities
• Collaborate with cross-functional teams to optimize manufacturing processes and improve efficiency
• Partner with Quality and other departments to assess deviations, determine root cause and execute preventive and corrective action
• Accurate and timely recording of work time by clocking in and out using designated timekeeping systems. Adherence to company timekeeping policies, including rules regarding overtime, meal breaks, and reporting procedures for any discrepancies.

Qualifications/Skills:

• High school diploma or GED and 2 years of relevant industry experience. Advanced degree in relevant field of study will be considered towards relevant industry experience.
• Builds trustful and effective relationships with authenticity and humility
• Confidence to work in a rapidly changing environment
• The ability to contribute to a team where employees have a shared purpose and vision; foster a “One Denali” environment
• Strong self-awareness of the impact communication and working style has on others
• Proficient verbal and written communication skills
• Physical – must be able to put on specialized gowning, lift and manipulate items over 25 lbs, climb ladders, stand for multiple hours at a time
• Must be able to wear personal protective equipment (e.g., safety shoes, gloves, eye covering, etc.) in a compliant manner for extended periods of time
• Must be able to work Monday through Thursday shift.

Preferred Qualifications

• Previous manufacturing experience in a regulated industry.
• Experience in product/process support within a regulated setting
• Experience with Good Documentation Practices and Good Manufacturing Practices.

Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

• Responsibilities span across media and buffer preparations for production campaigns. This includes, but is not limited to, media and buffer preparation, set-up and take-down of equipment and single-use assemblies, and both testing and actual operations.
• Introduction to unit operations as requested which include but not limited to cell culture and purification processes.
• Document all manufacturing activities accurately and comprehensively in batch records and document all non-conformance issues
• Conduct all activities in accordance with company policies & Standard Operating Procedures, global regulatory guidelines, environmental guidelines, as appropriate, etc.
• Remain up to date on all assigned training and ensure completion of any training required for GMP activities prior to executing those activities
• Collaborate with cross-functional teams to optimize manufacturing processes and improve efficiency
• Partner with Quality and other departments to assess deviations, determine root cause and execute preventive and corrective action
• Accurate and timely recording of work time by clocking in and out using designated timekeeping systems. Adherence to company timekeeping policies, including rules regarding overtime, meal breaks, and reporting procedures for any discrepancies