EXPERIENCE REQUIRED:

• PhD with experience in oncology drug development required.
• 2+ years of experience in drug development in pharmaceutical or biotech industries
• In-depth knowledge of Immunology, Haematology-Oncology disease area biology and translational science.
• Prefer expertise in myeloma, leukemia and lymphoma.
• Highly desired experience with cell therapy, T cell engagers, and antibody-drug conjugates modalities is preferred
• Proven communication, presentation and influencing skills.
• Highly developed problem solving and risk management skills.
• Ability to drive, manage, execute and deliver results for complex multi-functional projects.
• Highly developed collaborative working skills.
• Ability to act as an external ambassador and to influence external organizations to enhance the image and reputation of AstraZeneca.
• Proven ability to motivate and develop others.
  The annual base pay for this position ranges from $134,578.00 to $201,868.00. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
  When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
  At AstraZeneca, you’ll find an environment that fosters innovation and growth. Our entrepreneurial spirit combined with the security of a global pharma ensures that you can define your career path while making a significant impact. We are committed to protecting our patients, our people, and our planet. Here, you are encouraged to take ownership, develop new skills, and expand your capabilities. Our culture is rooted in integrity, inclusiveness, and dedication to supporting communities worldwide. Join us as we inspire change with integrity and celebrate diversity.
  Global job cod

• Develop and implement comprehensive translational science strategies encompassing patient selection, pharmacodynamics, mechanism of action, and mechanism of resistance for preclinical therapies through Phase 3 clinical studies
• Deliver robust biomarker strategies and data for clinical studies based on best available science and technologies
• Accountable for development and deployment of fit for purpose translational assays both internally and or externally
• Measure target engagement, pharmacodynamic biomarkers, and mechanism of action reliably and quantifiably to inform clinical decisions.
• Explore mechanisms of resistance of therapies and deliver data to guide decision making
• Implement translational strategies into clinical studies, including sample collection protocols, laboratory manuals, clinical study protocols, and biomarker analyses in oncology and haematology studies.
• Analyze target expression, cancer pathway interactions, feedback mechanisms, and tumor microenvironment features in clinical samples to guide rational drug combination strategies across oncology and haematology programs.
• Contribute to and ensure quality of Translational Medicine clinical study reports, data reviews and interpretations, presentations, scientific publications, and recommendations to development teams and management for strategic decision-making.
• Collaborate with cross-functional teams including Oncology Research, Translational Medicine, clinical development, clinical operations, and product development teams to facilitate appropriate incorporation of translational medicine strategies for molecules in early phases of development.
• Influence translational strategy across the AstraZeneca portfolio to maximize scientific impact and therapeutic outcomes.
• Lead and manage internal and external research collaborations in areas of clinical technologies and oncology translational research to advance portfolio objectives.