Associate Scientist, Downstream Process Development

at  Johnson Johnson

Johnson and Johnson is currently seeking an Associate Scientist, Downstream Process Development located in Malvern, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong.
The Associate Scientist will support early and late phase process development of harvest clarification, protein purification, viral filtration, and ultrafiltration/diafiltration steps of the downstream process at the Malvern, PA site. They will also provide support for technical transfer to different manufacturing facilities and any required technical support for manufacturing investigations or regulatory filings.

Primary responsibilities:

• Participate in design of experiments of harvest clarification, protein purification, viral filtration, and UF/DF
• Perform study execution
• Document experimental execution
• Record and analyze data
• Maintain accurate laboratory documentation and author technical reports
• Participate in tech transfer, facility fit, and process scale up/ scale down
• Support early Technical Transfer activities through generation of protocols/reports, technical writing, and execution of laboratory scale studies
• Support “process fit to plant” during early stages of development to provide guidance to both development and manufacturing teams
• Support “person in plant” by providing support during manufacturing campaigns for new product introduction (NPI) campaigns
• Participate in scientific investigations and trouble-shoot process issues that arise during development, technology transfer, or scale-up
• Contribute to regulatory filings
• Effectively work in a team environment as well as contributing individually to meet project objectives and timelines
• Other duties will be assigned, as necessary

QUALIFICATIONS

Education:

• Minimum of a Bachelor’s degree in Chemical Engineering, Biological Sciences, or related scientific field is required

Required:

• Minimum of 2 years of proven experience
• Experience maintaining written records of work in the form of laboratory notebooks (paper or electronic)
• Highly organized and capable of managing/pursuing multiple projects with some supervision
• Good written and verbal communication skills
• Excellent interpersonal skills with adaptability to rapid changes in project priorities and requirements
• Acute attention to detail
• Skills to report data and present findings to management
• Occasional weekend work is required

Preferred:

• Hands-on experience performing large molecule drug substance (API) downstream manufacturing process development
• Experience with protein purification platform e.g. AKTA system

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability

• Participate in design of experiments of harvest clarification, protein purification, viral filtration, and UF/DF
• Perform study execution
• Document experimental execution
• Record and analyze data
• Maintain accurate laboratory documentation and author technical reports
• Participate in tech transfer, facility fit, and process scale up/ scale down
• Support early Technical Transfer activities through generation of protocols/reports, technical writing, and execution of laboratory scale studies
• Support “process fit to plant” during early stages of development to provide guidance to both development and manufacturing teams
• Support “person in plant” by providing support during manufacturing campaigns for new product introduction (NPI) campaigns
• Participate in scientific investigations and trouble-shoot process issues that arise during development, technology transfer, or scale-up
• Contribute to regulatory filings
• Effectively work in a team environment as well as contributing individually to meet project objectives and timelines
• Other duties will be assigned, as necessar