Associate Scientist, Gene Delivery and Editing Process Development at BristolMyers Squibb
Seattle, Washington, USA -
Full Time


Start Date

Immediate

Expiry Date

16 Nov, 25

Salary

88430.0

Posted On

16 Aug, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Unit Operations, Technical Writing, Chemical Engineering, Software, Statistical Software, Molecular, Virology, Mammalian Cell Culture, Chromatography, Biochemistry, Design

Industry

Hospital/Health Care

Description

WORKING WITH US

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

POSITION SUMMARY

We are seeking an enthusiastic, self-driven individual to join the Gene Delivery Process and Analytical Development team. Our team develops the end-to-end processes and technologies to deliver the critical raw materials used in the manufacturing of engineered T cells, including viral vectors. The primary focus of this Associate Scientist is to develop high-throughput tools to support process development, production, and characterization of viral vectors (lentiviral vectors and/or adeno-associated viruses) used for gene delivery and gene editing of our cell therapy products. This team member will support current programs and advance our capabilities in vector production.

Responsibilities:

  • Perform hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production.
  • Support process and technology development for viral vector manufacturing platforms utilizing suspension cell culture, transient transfection, purification, and single-use systems.
  • Support development of high-throughput process development tools such as automated multi-parallel bioreactor system (Ambr) and liquid handlers (ie. Tecan).
  • Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles. Manage and analyze large data sets.
  • Maintain proper documentation of experimental results using an electronic lab notebook
  • Summarize and present scientific data; communicate progress to project teams
  • Author technical documents including protocols and internal development reports
  • Maintain a safe work environment in accordance with policies/procedures/regulations.

Education:

  • M.S. or B.S. in Biological or Chemical Engineering, Virology, Molecular or Cellular Biology, Biochemistry, or related discipline

Qualifications:

  • 0-2 years of hands-on experience with biological process unit operations and equipment with working knowledge of mammalian cell culture, bioreactors, chromatography, normal flow filtration, tangential flow filtration, high-throughput automation
  • Uses scientific principles and engineering fundamentals to solve problems
  • Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)
  • Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team
  • Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on the lives of patients with serious diseases
  • Ability to communicate clearly and concisely through oral presentation and technical writing
  • Familiarity with process control principles and software as well as programming automated equipment

The starting compensation for this job is a range from $91 ,830 - $111,300, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

How To Apply:

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Responsibilities
  • Perform hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production.
  • Support process and technology development for viral vector manufacturing platforms utilizing suspension cell culture, transient transfection, purification, and single-use systems.
  • Support development of high-throughput process development tools such as automated multi-parallel bioreactor system (Ambr) and liquid handlers (ie. Tecan).
  • Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles. Manage and analyze large data sets.
  • Maintain proper documentation of experimental results using an electronic lab notebook
  • Summarize and present scientific data; communicate progress to project teams
  • Author technical documents including protocols and internal development reports
  • Maintain a safe work environment in accordance with policies/procedures/regulations
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