Title: Associate Scientist – iPSC-Derived Neuron Models
Location: 33 Hayden Ave, Lexington, MA, 02421
Duration: 1 Year (Contract)
Work Arrangement: Onsite, 5 days/week
Openings: 1
Candidate Level: Must specify Level II or Level III in submission notes for consideration

POSITION SUMMARY

We are seeking a highly motivated and detail-oriented Associate Scientist to join our Humanized In Vitro Model Development team. The successful candidate will play a key role in developing and applying human iPSC-derived neuronal models and assays to support drug discovery and translational research. This role offers an opportunity to work at the cutting edge of human-relevant neuroscience within a collaborative and innovative environment.

QUALIFICATIONS:

• Education: Bachelor’s or Master’s degree in Neuroscience, Cell Biology, Stem Cell Biology, or a related field.
• Experience Levels:
• Level II: Minimum 3 years professional experience with at least 2 years hands-on work with human iPSC-derived neuronal cell models and assays.
• Level III: Minimum 5 years of hands-on experience with human iPSC-derived neuronal cell models and assays.
• Core Skills (Required):
• Expertise in human iPSC-derived neuron culture.
• Experience with gene perturbation techniques (siRNA and/or CRISPR).
• Proficiency in at least 2–3 of the following:
• qPCR
• Immunocytochemistry
• Micro-electrode array (MEA)
• Fluorescence microscopy

PREFERRED SKILLS:

• Experience with CRISPR editing, RNA-seq, calcium imaging, high-content imaging, or complex co-culture systems.
• Knowledge of automated liquid handling systems and high-throughput screening platforms.
• Familiarity with cardiometabolic diseases is a plus.
  HL01
  Job Type: Contract
  Pay: $44.73 - $51.44 per hour

Ability to Commute:

• Lexington, MA 02421 (Preferred)

Ability to Relocate:

• Lexington, MA 02421: Relocate before starting work (Preferred)

Work Location: In perso

• Culture, differentiate, and maintain human iPSC-derived neurons.
• Perform molecular and cell-based assays such as:
• Immunocytochemistry
• qPCR