REQUIRED QUALIFICATIONS & EXPERIENCE

• MSc in Biochemistry, Molecular Biology, or a related field, with 3+ years of industry experience, OR
• PhD in a relevant field with 1+ years of industry experience.
• Proficiency in generating and working with large datasets, including transcriptomic, proteomic, or metabolomic datasets.
• Experience developing high-throughput methods (e.g., HT NGS) for automated target discovery pipelines.
• Familiarity with bioprocess-relevant cell lines such as CHO or HEK293 for monoclonal antibody production and characterization.
• Expertise in mammalian cell culture techniques, including passaging, banking, transfection, nucleofection, and genotyping.
• Experience with mammalian cell line development, including GM/GE cell lines, single-cell cloning, and CRISPR/ORF library screens.
• Skilled in molecular biology techniques, including FACS, qRT-PCR, Western blot, and ELISA.
• Strong experimental design and troubleshooting skills.
• Proven ability to work independently and collaboratively within a team.
• Experience planning experiments and meeting project timelines.
• Strong numeracy, computer literacy, and communication skills.
• Desirable Experience:
• Familiarity with analytical methods such as HPLC/UPLC and LC-MS for antibody characterization.
• Knowledge of experimental techniques such as metabolic flux analysis (MFA).
• Experience applying Design of Experiments (DOE) principles to optimize experimental designs.

KEY SKILLS AND ATTRIBUTES:

• Innovative and solutions-oriented mindset.
• Advanced problem-solving abilities.
• Self-motivated with a proactive approach.
• Results-driven with a commitment to high-quality outcomes.
• Reliable and organized, with the ability to multitask effectively.
• Strong time management and organizational skills.
• Excellent written and verbal communication skills.
• Team-oriented and adaptable within a dynamic, multidisciplinary environment.
  This role offers an exciting opportunity to contribute to ground breaking research and development in the field of bioprocessing and immunotherapeutics.

THE ROLE:

This position focuses on supporting and executing multi-omics workflows as part of a collaborative team. The goal is to develop the next generation of mammalian expression systems and cell lines to enable efficient pharmaceutical bioprocesses and cost-effective immunotherapeutics.

KEY RESPONSIBILITIES:

• Design and contribute to the generation and interpretation of multi-omics datasets to advance cell line characterization and target discovery pipelines.
• Develop, optimize, and implement high-throughput sample preparation methods, including next-generation sequencing (NGS), transcriptomics, and other advanced analytical assays to accelerate research.
• Perform mammalian suspension cell culture and related techniques, such as passaging, banking, nucleofection, and genotyping, as well as assays including western blotting and FACS.
• Prepare and maintain key project deliverables, including SOPs, training documents, and COSHH forms.
• Train team members to a high level of competency to ensure data integrity.
• Accurately document research findings in laboratory notebooks.
• Present findings regularly in group meetings and provide updates to project teams and stakeholders.
• Contribute to routine laboratory maintenance, including equipment care, cleaning schedules, and consumables management.
• Share responsibility for out-of-hours cell culture maintenance.
• Adhere to and promote laboratory health, safety, and quality procedures.
• Assist with laboratory risk assessments and ensure compliance with safety protocols.
• Maintain project confidentiality and ensure adherence to protocols.
• Stay updated on new technologies and relevant scientific developments to identify potential improvements and cost-reduction opportunities.