Associate – Vector Biology– Lilly Gene Therapy at Lilly

Boston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

02 Jan, 26

Salary

187000.0

Posted On

04 Oct, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Molecular Biology, Cell Biology, Lentiviral Vector Production, Quality Control, Flow Cytometry, Sequencing, Transfection, Titration, Functional Assays, Genome Editing, CRISPR, Recombinase, Primary Cell Engineering, Troubleshooting, Collaboration, High-Throughput Testing

Industry

Pharmaceutical Manufacturing

Description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Join the rapidly expanding Lilly Gene Therapy team at Eli Lilly. We invent, characterize, and advance novel gene therapy reagents for a wide range of clinical applications, working cross-functionally across disease areas and platforms. Our goal is to deliver on the promise of gene therapy for patients worldwide. Responsibilities Design, produce, and characterize lentiviral vectors (LVVs) to support discovery-stage cell therapy programs. Develop and execute small-scale LVV production workflows to enable high-throughput testing of CAR and other construct panels. Perform quality control and titering using molecular and cellular assays, including qPCR, ddPCR, flow cytometry, and sequencing. Optimize LVV packaging and transduction protocols to improve yield and consistency. Maintain detailed experimental records and contribute to data analysis and troubleshooting. Collaborate with internal teams to support in vitro and in vivo evaluation of engineered constructs. Basic Qualifications Bachelor’s degree with 3+ years, or Master’s degree with 1+ years of relevant laboratory experience in molecular biology, cell biology, or related field. Preferred Skills Experience with high-throughput LVV production workflows and automation platforms is a plus. Familiarity with genome editing tools (e.g., CRISPR, recombinase) for site-directed integration is a plus. Experience with primary cell engineering and/or functional screening assays; in vivo study experience is a plus. Strong troubleshooting skills and ability to work in a collaborative, fast-paced environment. Hands-on experience with lentiviral vector production, packaging, and characterization. Proficiency in molecular biology and cell culture techniques, including transfection, titration, and functional assays. Familiarity with quality control methods such as qPCR/ddPCR, flow cytometry, and sequencing. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

Responsibilities

Design, produce, and characterize lentiviral vectors to support discovery-stage cell therapy programs. Collaborate with internal teams to support in vitro and in vivo evaluation of engineered constructs.