Spectrix Analytical Services, LLC is seeking full-time permanent Bioanalytical Scientists to support pharmacokinetic (PK) assay development using the MSD (Meso Scale Discovery) platform in a fast-paced Immunogenicity Sciences group at our client site located in Andover, MA.
The Immunogenicity Sciences group is a dynamic industry-leading team whose mission is to identify key risks associated with unwanted clinical immunogenicity and influence drug design to mitigate those risks. This is accomplished through a suite of cell-based assays geared towards assessing and predicting unwanted immunogenicity of biotherapeutics. These assays enable the group to make data-driven recommendations through molecular design, making therapies safer while maintaining efficacy to treat the intended disease.
The ideal candidate will have hands-on experience designing and executing both ligand-binding assays (e.g., ELISAs, MSD, Gyrolab) to measure drug concentrations for PK analysis, and cell-based assays to assess immune responses and support immunogenicity risk evaluation.
The Scientist will design, develop and implement ligand-binding assays to measure the protein concentration of drug and/or biomarker and detect the presence of anti-drug antibody in a fast paced and dynamic environment. They will perform data analysis, data interpretation, and draw conclusions regarding progress and results of their work, utilizing the data for appropriate decision making. They will gather input from colleagues, literature, and additional resources to assist in project advancement.

QUALIFICATIONS:

• BSc with at least 2+ years relevant experience or MSc with at least 1+ year relevant experience with a focus on protein ligand-binding assay development (This is a NON-PhD position)
• Detailed knowledge and hands-on experience executing laboratory experiments utilizing various platforms and analytical problem-solving skills
• Ability to author technical documents such as data summary reports and analytical procedures
• Strong organizational, time management, and collaborative skills
• Proven presentation skills
• Collaborate effectively within a team environment to meet project timelines and quality standards
• Extremely well-organized with a high attention to detail
• Ability to rapidly familiarize with various equipment, instrumentation, and software; rapid learner
  *Spectrix offers flexible schedules, competitive salaries, and a committed work environment to its employees; the company provides automatic benefits of life insurance and short and long term disability insurance. Optional benefits for full time employees include health, dental, and vision insurance, college loan assistance, and an employer matched retirement savings plan. Spectrix is not a placement agency.
  Spectrix is an equal-opportunity employer. We do not discriminate on the basis of race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Spectrix complies with all applicable federal, state, and local laws governing nondiscrimination in employment.
  Spectrix is participating in the E-Verify program of the U.S. Department of Homeland Security (phone number: 888-897-7781, and website: www.dhs.gov/E-Verify).
  Job Type: Full-time
  Pay: $32.00 - $42.00 per hour
  Expected hours: 40 per week

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Employee assistance program
• Flexible spending account
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Professional development assistance
• Referral program
• Tuition reimbursement
• Vision insurance

Ability to Commute:

• Andover, MA 01810 (Required)

Ability to Relocate:

• Andover, MA 01810: Relocate before starting work (Required)

Work Location: In perso

• Design custom experiments, modify experimental conditions, troubleshoot problems, validate, and conduct ligand-binding assays (e.g. ELISAs, MSD, Gyrolab) to support biotherapeutic programs.
• Design and execute non-standard MSD, ELISA, and Gyrolab experiments to determine quantitative PK/PD information for a variety of protein and antibody targets.
• Deliver concentration and immunogenicity data to BioMedicine Design Project Leads and other Biotherapeutics partners.
• Documentation of experimental results utilizing electronic notebooks or study reports.