Bioconjugation Scientist at Eurofins

Louisville, Colorado, United States -

Full Time

Start Date

Immediate

Expiry Date

08 Feb, 26

Salary

110000.0

Posted On

11 Nov, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Bioconjugation, Antibody-Drug Conjugates, Linker Design, Payload Design, Biochemical Assays, Experimental Design, Data Analysis, Data Interpretation, Protein Purification, UV-Vis, SEC, HIC, RP, IEX, cIEF, LC-MS

Industry

Medical and Diagnostic Laboratories

Description

Company Description The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break into the biopharmaceutical industry and grow from the bottom up. We have the supportive teams and tools available to invest in you while also affording you work-life balance and a competitive benefits package. Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies. If you’re looking for a rewarding career, a place to call home, apply with us today! Job Description Position Summary: This role will support Antibody-drug conjugates (ADCs) linker and payload design, develop conjugation technologies, and downstream biochemical assays to enhance ADC biological and pharmacologic properties. We are looking for a strong scientist with good knowledge and hands-on experience in designing, preparing, and characterizing ADCs. This individual will be a self-motivated, responsible, and productive scientist who enjoys collaborating. They will be responsible for rigorous experimental design, data analysis, and data interpretation. This position requires excellent people skills, a positive can-do attitude, and the ability to thrive in a highly interactive, fast-paced, team environment. Responsibilities: Prepare, purify, and characterize the high-quality antibody-conjugates (ADCs, ARCs, DACs etc.) with a high degree of independence in support of discovery and development of programs. Implement state of the art bioconjugation technologies (cysteine, lysine, site-specific and other) and utilizing other bioorthogonal chemistries to generate bioconjugates. Experienced in development of purification strategies (up to 100 mg) with affinity, ion-exchange, hydrophobic interaction, size exclusion, and tangential flow filtration. Maintain thorough documentation of experimental procedures in electronic notebook or database, writing of reports and technical documents. Engagement with multidisciplinary project teams to execute and interpret experiments. Participate and present periodic updates and reports to management team. Maintain a safe, pleasant, and efficient working environment. Qualifications Basic Requirements: A minimum of a master’s degree in chemistry, biochemistry, or other related scientific discipline with a record of minimum 2 years in an industry lab-based independent research experience is required. Deep expertise in using state-of-the-art conjugation methods and handling of potent linker-payloads. Experienced in ADC characterization methods, including UV-Vis, SEC, HIC, RP, IEX, cIEF, and LC-MS. Must be eligible to work in the United States indefinitely without restriction or sponsorship. Additional Preferences: Experience with protein purification systems is preferred with hands-on experience and proficiency working with AKTA FPLCs. Must be highly collaborative and able to effectively engage small-molecule research project teams to make rapid progress. Demonstrated ability to work well with other accomplished professionals within and across functions/teams. Ability to multi-task and shift priorities rapidly to meet tight deadlines. Excellent written and verbal communicator. Detail oriented and well organized. Enthusiastic, self-motivated, and keen to improve processes. Additional Information Position is Full Time, Monday – Friday, 8am-5pm with overtime as needed. Candidates currently living within a commutable distance of Louisville, CO are encouraged to apply. Excellent full-time benefits include: Comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holiday Yearly goal-based bonus & eligibility for merit-based increases Compensation: $90,000-$110,000 per year based on experience Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Responsibilities

The Bioconjugation Scientist will support the design and development of antibody-drug conjugates (ADCs) and implement bioconjugation technologies. Responsibilities include preparing and characterizing high-quality ADCs and engaging with multidisciplinary project teams.