Site Name: UK - Cambridgeshire - Addenbrookes
Posted Date: Aug 20 2025
We are seeking a highly motivated laboratory scientist to join the Clinical Biomarker Laboratory, in the Biomarker and Bioanalytical Platforms (BBP) department based at the GSK Clinical Unit (CUC) in Cambridge, UK. The successful candidate will work as part of a team that provides Biomarker sample study support by working with multiple different sample types/matrices from FTIH, Enabling and Translational Studies, and interventional clinical studies in a GCP regulated laboratory.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

QUALIFICATIONS & SKILLS:

We are looking for professionals with these required skills to achieve our goals:

• BSc or MSc degree (or equivalent) in biological sciences or a relevant scientific field.
• Prior experience or understanding of working in a GCP setting.
• Strong laboratory experience and expertise working with a variety of sample types including whole blood, PBMC, single-cell tissue suspensions or tissue biopsies, which may be infected with blood-borne pathogens such as HBV.
• Ability to maintain a disciplined approach, ensuring a relentless focus on quality, compliance, and operational excellence even when flexing between multiple projects.
• Be a highly motivated team player with the ability to interact effectively within a multi-disciplinary team but also the confidence to work independently to tight deadlines.
• Good judgment and decision making, especially for prioritising multiple requests with the ability to problem solve and troubleshoot.
• Track record of delivering high quality, in a timely fashion with a positive can-do and attitude.

PREFERRED QUALIFICATIONS & SKILLS:

If you have the following characteristics, it would be a plus:

• A good understanding of the drug development process.
• Strong laboratory experience and understanding of clinical and non-clinical biomarker assays.
• Experience of writing SOPs and other regulated documents.
• Effective communication and teamwork skills.

CLOSING DATE FOR APPLICATIONS: 3RD SEPTEMBER 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

As a lab-based scientist, you will:

• Develop biomarker assays and generate high quality samples received directly from the Clinical Unit and other sources, examples to include:
• PBMC from fresh whole blood.
• Fresh whole blood stimulations (e.g. plate-based assays or TruCulture Tubes) and subsequent plasma harvesting.
• Preparation of fresh tissue samples to FFPE block, sectioning and the use of automation to stain and scan histological sections.
• Process fresh cellular samples, blood, PBMC to prepare single cell preparations suitable for downstream molecular quantification, including relevant QC testing.
• Generate high quality data from fresh whole blood or PBMC (real time) to support FTIH, Enabling & Translational, and interventional clinical studies by spectral flow cytometry (Cytek Aurora) including sample preparation and sample acquisition.
• Demonstrate innovation and the capacity to learn and evaluate new biomarker techniques and methodologies.
• Handle human biological samples and perform experimental work in accordance with GCP and Human Tissue Act (HTA) regulations, environmental safety assessments and data integrity guidelines.
• Work as part of the team to ensure day-to-day laboratory responsibilities are met, including co-ordinating maintenance of laboratory equipment and performing regular end-user maintenance activities.
• Available for occasional out of hours study support when required.
• Function well with and have clear lines of communication across multiple other groups within the CUC, for example the Clinical Processing Laboratory, the Clinical Ward, the Clinical Development Managers.
• Act as a contact between the Clinical Biomarker Laboratory and teams not based at the CUC, for example with other groups within BBP, Respiratory, Immunology and Inflammation Research Unit (RIIRU), Oncology Research Unit, etc.
• Closely collaborate and provide lab support and sample analysis for the biomarker assay team at Stevenage as needed.
• Strong attention to detail and production of high-quality electronic laboratory notebook write ups.