ABOUT US:

BrainXell is a growing biotechnology company that provides high-purity, iPSC-derived human neurons, astrocytes, and microglia for translational research and drug discovery. Utilizing proprietary technology, we generate a variety of assay-ready, subtype-specific cells of the CNS, relevant to a range of neurological disorders. Each cell subtype can be produced from unique iPSC lines into custom batches ranging from 50 million to 10 billion viable cells. BrainXell is dedicated to delivering the highest quality cells while fostering a vibrant and collaborative work environment where talented individuals can thrive and make a meaningful impact.

POSITION SUMMARY:

We are seeking an experienced and motivated Cell Culture Scientist IV to join our team. In this role, you will play a crucial part in the production and optimization of iPSC-derived cell lines, contributing to the advancement of our research and product development. Your expertise in cell culture techniques will support our mission to provide high-quality cells for use in translational research and drug discovery.

QUALIFICATIONS:

• Bachelor’s Degree in Cell Biology, Neuroscience, or a related discipline and 4+ experience or,

• Relevant Certificate and 5+ years’ experience or,

• 6+ years’ industry experience

• Proven experience with iPSC maintenance and differentiation, neural differentiation preferred

• Proficiency in flow cytometry, qPCR, ICC, and sequencing or,

• At least 1 year of relevant assay experience

• Proficiency in or experience with:

• Aseptic technique

• Scientific documentation
• Data analysis

SKILLS & COMPETENCIES:

• Excellent communication skills, with the ability to clearly convey complex information (e.g., complex phenotypes, functional assays, reproducibility, and experimental results).
• Ability to work both independently and collaboratively in a fast-paced cross-functional team environment.
• Strong organizational and time management skills
• Independently plan and manage time to meet production schedule
• Demonstrate effective mentorship for less experienced team members
• Ability to perform occasional weekend work, as required.

• Optimize and maintain cell culture protocols for various CNS cell types, including neurons, astrocytes, and microglia.
• Lead iPSC onboarding and culture efforts, including both feeder-free and feeder-dependent systems.
• Generate and validate high-purity iPSC-derived cell lines from unique iPSC sources.
• Perform reprogramming and transfection techniques to support iPSC line development and downstream differentiation.
• Conduct experiments to assess cell viability, differentiation, and functional characteristics.
• Collaborate with interdisciplinary teams to design and execute research projects aligned with organizational goals.
• Analyze data, prepare technical reports, and present findings to internal stakeholders.
• Ensure compliance with laboratory safety and quality standards, maintaining thorough and accurate documentation.
• Stay informed on emerging trends and contribute to the development and implementation of innovative methodologies.