KEY REQUIREMENTS:

• BSc/MSc Degree in Life Sciences, Molecular Biology, or a related field.
• Practical experience within R&D in industrial or academic settings.
• Hands-on experience in mammalian cell culture, stable transfections, single cell insolation and bioreactor operations (experience with Beacon and Ambr®15 is highly desirable).
• Strong analytical and problem-solving skills, with the ability to manage multiple experiments in parallel.
• Familiarity with implementation/development of automation for cell line screening & CLD process optimisation.
• A proactive attitude to working and solving challenging problems

THE ROLE:

We are recruiting a Scientist with a background in cell expression technologies to join our R&D Cell Engineering and CLC group at our Cambridge site. This is an outstanding opportunity to be at the forefront of developing next-generation, industrially relevant cell expression platforms.
This is an excellent opportunity to play a key role in advancing expression systems and services for the efficient production of complex therapeutic proteins and contributing to world-class scientific breakthroughs!

KEY RESPONSIBILITIES:

• Contribute to the delivery of new CHO-based mammalian expression hosts and vector systems for the expression of complex therapeutic proteins
• Explore innovative ideas to optimise the cell line development (CLD) process including the use of automation equipments & novel technologies
• Culture mammalian cell lines in flasks and small-scale bioreactors and perform analytical procedures as required by the project
• Plan, execute, and monitor experiments using the Ambr®15 automated bioreactor platform
• Troubleshoot technical issues with the Ambr®15 system and liaise with vendors/technical support as needed
• Collate, analyse, evaluate and sign-off data to produce good quality information and traceable records under the direction of the project lead.
• Support the development of study plans & other relevant documents
• Present results in written and oral reports.
• Actively keep abreast of relevant academic literature (e.g., in the field of cell engineering and expression technologies)
• Contribute ideas and opinions to scientific discussions to aid the development of new technologies
• Working as a team player and working with a high degree of flexibility