Re:Cognition Health is a pioneering brain and mind clinic that specialises in the treatment and care of people showing symptoms of cognitive impairment. Utilising the latest progressive medical research and evidence-based treatments, we are passionate about transforming and optimising cognitive performance through education, clinical excellence and by providing access to emerging treatments.
The Re:Cognition Health Clinics in London, Winchester, Surrey, Birmingham, Guildford, Plymouth, Bristol and Washington DC are also major centre’s for international trials of disease-modifying and new symptomatic drugs for Alzheimer’s disease and other neurological conditions in adults and children. Our multi-disciplinary team work collaboratively to provide a full service, patient-centred approach using the latest progressive medical research and evidence-based treatments.
We value people who share the same passion for research, dedication to their area of expertise, are hardworking and want to be part of our growth and success.
We are seeking a Clinical Trials Sub Investigator for our Bristol clinical research site to support clinical trials investigating innovative treatments for mental health disorders.
The ideal individual is a dedicated, hardworking individual with experience in cognitive disease and clinical research. Unique opportunity for individuals looking for an opportunity to take on a range of responsibilities and grow with the company. This is a full-time position. The candidate must be a GMC registered doctor.
The successful candidate will be provided the opportunity and supported by Re:Cognition Health, to undertake the 4 year Pharmaceutical Medicine Specialty Training (PMST) to receive a CCT in pharmaceutical medicine from the Faculty of Pharmaceutical Medicine. Re:Cognition Health is a recognized training centre for PMST.
Re:Cognition Health is a GMC Designated Body but the candidate would transfer to the Deanery for revalidation if undertaking PMST.

ROLE:

The primary responsibility of the sub-investigator is to ensure the well-being, safety and interests of all participants, at your centre, taking part in clinical trials. The Principal Investigator has overall responsibility for the conduct of the clinical trials and will delegate specific duties to an appropriately trained and qualified Sub-Investigator.

KEY OBJECTIVES AND RESPONSIBILITIES:

• Working under the direct supervision of the Principal Investigator to perform the clinical trials in accordance with ICH GCP (R2).
• Ensure complete understanding of the clinical trial protocol(s) to provide complete information and explanation to potential participants, to obtain written informed consent.
• Undertake and oversee the medical screening for potential participants. Including ECGs, vitals, venepuncture and lumbar puncture, to ensure they meet the entry requirements of each clinical trial protocol.
• With the PI, consider the participant’s eligibility for each clinical trial protocol, according to the specific inclusion and exclusion criteria, prior to randomisation.
• Perform ongoing follow up assessments, including clinical examinations (physical/neurological examinations, ECGs, vital signs, bloods) and dosing procedures as appropriate to each study (e.g. cannulation, IV, sub-cutaneous or oral dosing).
• Review and evaluate Vital Signs, ECGs, and Laboratory test results etc. for all studies, ensuring that any clinically significant abnormal results and/or changes from baseline are reported, and action taken to the Principal Investigator, Medical Monitor, and/or Sponsor contacts.
• Represent Re:Cognition health and the site, during sponsor led meetings, including pre-site selection, site imitation and onsite monitoring visits, providing essential medical input.
• Lead on the resus equipment checking and medical emergency scenario training at the site.
• Provide support to the central recruitment team, in the capacity of a research physician.