Co-op, Biology Drug Discovery at Blueprint Medicines

Cambridge, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

29 Dec, 25

Salary

35.0

Posted On

30 Sep, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Molecular Biology, Cell Culture, Assay Development, Data Analysis, Experimental Design, RNA Interference, Gene Editing, Western Blotting, Immunofluorescence, Cell Proliferation Assays, Viability Assays, High Content Imaging, Collaboration, Communication, Organizational Skills, Analytical Skills

Industry

Biotechnology Research

Description

Co-op, Biology Drug Discovery Address: 45 Sidney Street Cambridge, MA, 02139 Blueprint Medicines, a Sanofi company, is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients' lives by solving important medical problems, with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines, including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in the U.S. and Europe. Leveraging our established research, development, and commercial capability and infrastructure, we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. Responsibilities: We are seeking a motivated graduate-level co-op student interested in contributing to our drug discovery programs, with a focus target validation and assay development for testing candidate drug compounds. This student will apply advanced molecular biology techniques to evaluate candidate compounds and contribute to the scientific direction of our programs. Projects will be crafted along one or multiple of the following key areas based on interest and business needs: Lab Work: Design, execute, and analyze in vitro cellular assays across a variety of cell lines to assess drug efficacy and biological impact Perform mechanism of action studies on human and engineered cell lines, including proliferation assays, signaling assays, protein-protein interactions, and high content imaging assays Maintain cell cultures, generate stable cell lines using RNA interference (RNAi) or gene editing techniques (CRISPR/Cas-9) Execute drug combination studies on cell lines of interest to evaluate synergistic or antagonistic effects. Data Analysis and Documentation: Analyze experimental data using GraphPad Prism, Excel, and other relevant tools Maintain accurate and detailed electronic laboratory notebooks in compliance with Blueprint Medicines’ standards Collaboration and Communication: Participate in regular team meetings, present findings, and contribute to scientific discussions Collaborate with cross-functional teams, seek feedback, and actively contribute to a culture of innovation Perform other duties as assigned. ONSITE EXPECTATIONS: This is a lab-based position, and the Co-op is expected to work onsite 5 days/week. Qualifications: Currently enrolled student pursuing a PhD or master's program in biomedical sciences, molecular biology, or related field 1-2 years of independent laboratory research Strong foundation in cellular and molecular biology Proficiency in core lab techniques (e.g., tissue culture, Western blotting, DNA/RNA extraction, immunofluorescence, cell proliferation and viability assays, experience generating cell lines a plus) What additional qualifications will make you a stronger candidate? Strong commitment to pursuing a career in research Excellent communication, organizational, and analytical skills Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism Our Co-op Program: Blueprint’s Co-op program is ~6 months long. The program is designed to provide students with deep functional expertise within their department and a broad understanding of the life sciences industry. Co-ops are paired with dedicated mentors for personalized learning and career development guidance. The program includes lunch and learn sessions, networking events, a student volunteer day, and other networking opportunities. It culminates in a final poster presentation where interns showcase their work. Dress Code: Blueprint’s offices are a business casual environment. Business casual means attire that is professional but also relaxed, such as slacks or business dress pants, skirts/dresses, khakis, chinos, or dark jeans without holes paired with button-down shirts, sweaters, blouses, or polo shirts and closed-toed shoes. It typically excludes formal suits or very casual clothing such as athletic wear or flip flops. Spring 2026 Co-op Program Dates: Monday, January 5th – Friday, June 26th Pay Range: Our Co-ops are paid hourly based on previous Co-op experience. The expected pay range for this role is $32.00 - $35.00per hour. Who will my employer be? You will be employed by Magnit, LLC for all purposes and not Blueprint Medicines, a Sanofi Company. As your employer, Magnit will assign you to provide services to Blueprint as a co-op or intern. Under this arrangement, co-ops and interns will have the opportunity to learn about Blueprint Medicines, a Sanofi Company and gain meaningful hands-on experience. Please note: Co-op and interns are not employees of Blueprint in any way, and do not qualify for participation in Blueprint’s benefit plans. Equity, Diversity, Inclusion and Affirmative Action “To do our best work we need different viewpoints. Therefore, we celebrate diversity and embrace inclusion. As an equal opportunity employer, we are dedicated to building a team that represents a variety of backgrounds, perspectives, and skills. We strive to ensure that we maintain a positive and enriching work environment for all.” For more information on Magnit’s privacy notice, click on privacy notice. Magnit, LLC recognizes the importance of individually held beliefs re: appropriate dress/attire and will reasonably accommodate an employee’s religious beliefs unless the accommodation creates an undue hardship. Those requesting attire accommodation based on religious beliefs should reach out to their Magnit representative. Magnit is a Global industry leader with one simple goal of shaping and delivering the next chapter in workforce management for our employees, clients, suppliers, and partners around the world. Why Blueprint? At Blueprint Medicines, a Sanofi Company, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

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Responsibilities

The co-op student will contribute to drug discovery programs focusing on target validation and assay development. Responsibilities include designing and executing in vitro cellular assays, analyzing data, and collaborating with cross-functional teams.