Co-op, MSAT at STRAND THERAPEUTICS INC

Boston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

20 Jan, 26

Salary

28.0

Posted On

22 Oct, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics, mRNA, LNP, Chromatographic Purification, Filtration Methods, Biological Analytical Methods, LNP Formulation, Collaboration, Data Interpretation, Experimental Setup, Scientific Context

Industry

Biotechnology Research

Description

Company Overview: Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients. Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits. Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts. Become the next standout single strand! Job Summary: Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Co-op of MSAT. This is a fantastic opportunity to make a significant impact as a scientifically motivated self-starter capable of independently conceiving, conducting, and critically analyzing their own work with minimal supervision. Primary Responsibilities: Execution of experiments related to the advancement of Strands mRNA and LNP manufacturing and/or process optimization platforms. Carrying out the production and characterization of IVT synthesized mRNA. Support screening, optimization, and scale-up efforts for enzymatic reactions, chromatographic separations and filtration processes - including ultrafiltration, diafiltration, and sterile filtration. Carrying out the production and characterization of mRNA-LNP based formulations. Support the screening and optimization efforts for LNP mixing and downstream filtration processes. Working across diverse areas to support the group's development activities in a fast-paced and collaborative environment. Qualifications: On track to graduate with a B.S. or M.S. in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field. Experience in the biotechnology space is a plus. mRNA and/or LNP working experience is strongly preferred, but not a requirement. Basic knowledge of chromatographic purification and filtration methods for biologics. Experience with standard biological analytical methods (gel electrophoresis, ELISA, UV-Vis spectroscopy, etc.) Basic knowledge of LNP formulation and characterization methods (Ribogreen, DLS, etc.) Ability to follow standard operating procedures, make careful observations, maintain clear and complete records of lab work.‪ Strong collaboration and inter-personal skills. Ability to present scientific context, experimental set up, data interpretation, and big-picture conclusions to a diverse audience. Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates. Job Type: Intern Hourly Rate: $25-$28/hour

Responsibilities

The Co-op will execute experiments related to the advancement of mRNA and LNP manufacturing and process optimization. They will support various production and characterization efforts in a collaborative environment.