JOB DESCRIPTION

A temporary research assistant position (0.8-1.0 FTE) is available in the research group of Dimphna Meijer, Department of Bionanoscience, Delft University of Technology, the Netherlands. Starting date preferably between July – Sept 2025.
We are seeking an enthusiastic and computationally skilled individual to join our team as a cryo-EM support research technician on a temporary basis. This is an excellent opportunity for someone interested in the exciting combination of structural biology data processing, mammalian cell biology and lab management/organization.

ABOUT THE MEIJER LAB

Our group investigates how neurons form functional networks at the nanoscale, using an integrated approach that combines cell biology, biochemistry, and structural biology. Our work contributes to understanding the molecular basis of neurodevelopmental and neurodegenerative disorders. We address key questions such as:

• What is the structural basis of synapse formation
• How do pathogenic mutations disrupt protein architecture and function?

Recently, we have solved several cryo-EM structures of synaptic cell adhesion molecules to uncover the molecular recognition code of synapses. As our group expands, we are looking for additional support for cryo-EM workflows to support this research.
We are an international, multidisciplinary team aiming to understand the molecular mechanisms of neurobiology at the highest resolution. We value curiosity, teamwork, and a high-quality research culture. See also our group website www.dimphnameijerlab.org

JOB REQUIREMENTS

We are looking for a skilled and motivated research asssistant with a BSc/MSc degree in nanobiology, structural biology, biophysics or related field. We also consider applicants with a PhD degree. The ideal candidate enjoys efficiency, and is an excellent team player. You should be comfortable supporting data analysis pipelines in structural biology, but you should also be familiar with wet-lab workflows (e.g., mammalian cell culture, protein production). A strong sense of organization and an interest in lab management tasks such as ordering and safety procedures are essential. Experience with cryo-EM data processing (e.g., Relion 5, Cryosparc) is essential. We are happy to provide further training in cryo-EM data processing for motivated candidates with a strong interest in computational workflows.

Qualifications:

• BSc or MSc (or PhD) degree in a relevant field
• Demonstrable expertise with cryo-EM data processing and analysis
• Familiarity with mammalian cell culture
• Interested in maintaining a biological and chemical safe working environment
• Strong attention to detail and organizational skills
• Ability to work independently as well as part of a team
• Excellent communication and interpersonal skills

This position offers flexible working hours that can be tailored to the applicant’s needs. It is an ideal opportunity for someone who is considering an academic career path, a career in industry or a support position in a research facility.

• Structural bioloy data processing
• Mammalian cell biology
• General lab support (ordering, safety, organization)