Director, Biostatistics - Rare Disease at AstraZeneca

Santanyí, Balearic Islands, Spain -

Full Time

Start Date

Immediate

Expiry Date

29 May, 26

Salary

0.0

Posted On

28 Feb, 26

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Statistical Strategy, Program Leadership, External Engagement, Biostatistics, Regulatory Submissions, Technical Analysis, Cross-functional Collaboration, Team Management, Product Development, Preclinical Studies, Health Technology Assessment, Study Design, Benefit Risk Assessment, Global Leadership, CRO Partnership, External Representation

Industry

Pharmaceutical Manufacturing

Description

Are you ready to lead statistical strategy that accelerates life-changing medicines for people with rare diseases? Do you want to shape pivotal decisions with evidence that moves therapies faster and more confidently to patients? This is a high-impact role where your expertise will guide complex programs, steward external engagements, and elevate the craft of biostatistics across a global network. You will build capability, champion innovation, and drive rigorous standards that unlock speed and value without compromising scientific integrity. This is what you will do: The Director, Biostatistics has sufficient experience in the pharmaceutical industry to independently lead a biostatistics team to deliver project and/or technical level activities related to design, delivery and interpretation, high level internal governance committees and/or regulatory submissions. This individual is able to lead, perform and communicate results of more technical analyses, and able to guide and lead less experienced staff. Competent individual contributor with excellent cross-functional collaboration. You will be responsible for: To lead, manage and develop a group of statisticians Lead the statistical design and strategy to product development plans, preclinical studies, regulatory strategy, health technology assessment and/or commercial activities as appropriate for the stage of the product Lead the statistical content and ensure quality for study designs, documents, delivery and interpretation and submission Quantify the benefit, risk, value, and uncertainty of the emerging product profile and can communicate these effectively within the team Provide global leadership to others and direct project work delivered by internal and external staff Partner with CROs to ensure delivery to quality and time Represent Alexion externally which may include health authorities, advisory boards, conferences, workshops and/or payer interactions Maintain knowledge of statistical methodology in relevant areas and promote, investigate, and implement novel statistical approaches Represent statistical strategy and decision making at internal decision-making governance including review boards, therapy area leadership teams and ESPC/LSPC Mentor/coach and support the technical education and training of biostatistics staff Work according to agreed functional and regional Safety, Health and Environment (SHE) strategy by ensuring proper management of SHE risks, incidents, reporting, follow-up and improvements You will need to have: MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognized equivalent to stats MSc Track record of background in leading independently Exemplary technical skills Flexible, well-organized, and possess the ability to work well under pressure. The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have: PhD in Statistics/Biostatistics is preferred. At AstraZeneca's Alexion division for Rare Diseases you will find an environment where work is more than just a job—it's a mission. Our closeness to patients brings us closer to our work and each other. With a rapidly growing portfolio in a nimble biotech atmosphere supported by global resources, tailored development programs are crafted to improve your skills. These programs encourage a deep understanding of our patients' journeys. Here diversity is valued; inclusion is championed; innovation is celebrated; all while making a profound impact on patients' lives. Ready to make a difference? Apply now! Date Posted 27-Feb-2026 Closing Date 27-Mar-2026 Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.

Responsibilities

The Director will lead, manage, and develop a group of statisticians, taking charge of statistical design and strategy across product development plans, preclinical studies, regulatory strategy, and commercial activities. Responsibilities also include ensuring the quality of statistical content for study designs, documents, delivery, interpretation, and submissions, while quantifying product profile benefit, risk, value, and uncertainty.