Director, Cell Therapy Discovery at AstraZeneca

, , China -

Full Time

Start Date

Immediate

Expiry Date

10 Feb, 26

Salary

0.0

Posted On

12 Nov, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Strategic Thinking, Innovation Mindset, Project Management, Team Leadership, Molecular Biology, Cell Biology, Immunology, T-Cell Culture, CAR-T Product Design, Gene Editing, Flow Cytometry, ELISA, PCR/qPCR, Cross-Cultural Communication, Resource Management, Collaboration

Industry

Pharmaceutical Manufacturing

Description

Typical Accountabilities Strategic Planning & Execution: Develop long-term departmental goals and ensure alignment with the company’s overall R&D strategy. Lead and plan the strategic direction for product research and development. Support the Head of R&D in establishing management systems, development schemes, and operational processes. Product Development Guidance: Provide strategic and constructive input on R&D product planning. Offer insights and recommendations to senior management for decision-making. Support teams in troubleshooting and ensure timely delivery of all projects within defined timelines and quality standards. Budget & Plan Management: Develop and manage departmental R&D plans and budgets. Oversee the implementation and execution of R&D activities within the approved financial framework. Ensure effective cost control and on-time, on-budget completion of projects. Technology Innovation & Project Management: Lead the team in designing CAR-T products, developing new technologies, and filing related technical patents. Supervise project implementation within the department to ensure timely and high-quality delivery. Cross-functional Collaboration: Collaborate closely with Operations, Clinical, Regulatory Affairs, and Process Development teams to support project submission and product registration. Ensure smooth execution of company objectives and timely completion of R&D milestones. Academic Research & Reporting: Lead the company’s academic research initiatives and external R&D progress reports. Organize manuscript submissions to high-impact international journals and presentations at global conferences. Enhance the company’s academic influence and promote international recognition of technological achievements. Resource Integration & Partnership: Coordinate internal and external resources within the company and the broader group to meet R&D and business development needs. Build and maintain collaborations with external partners, research institutions, and regulatory authorities to drive project advancement. Leadership & Motivation: Lead, inspire, and empower the R&D team to achieve high performance and innovation excellence. Other Responsibilities: Perform other duties as assigned by senior management. Academic / Professional Qualification Ph.D. in Molecular Biology, Cell Biology, Immunology, or related biomedical disciplines with 8–10 years of relevant R&D experience in the biopharmaceutical industry; or Master’s degree with 12+ years of related R&D experience. In-depth expertise in T-cell culture and engineering, molecular biology techniques, flow cytometry, and cell purification. Strong proficiency in CAR-T product design, experimental design and execution, plasmid construction and purification, viral vector production and purification, T-cell transduction and gene editing, peripheral blood and T-cell isolation (MACS sorting), ELISA, proliferation assays, PCR/qPCR, multicolor flow cytometry, and tumor cell cytotoxicity assays in vitro and in vivo. Minimum 3 years of R&D project and team management experience. Technical / Skills Requirements Excellent strategic thinking and innovation mindset Strong global vision and ability to operate in an international environment Demonstrated excellence-driven and results-oriented attitude Profound insight into relevant scientific research areas Commitment to lifelong learning and continuous professional growth High self-motivation and initiative Strong cross-cultural adaptability and collaborative spirit Proven project management and team leadership capabilities Exceptional communication, coordination, and resource management skills Fluent in English, with strong cross-cultural communication and presentation abilities Date Posted 12-11月-2025 Closing Date 13-11月-2025 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Responsibilities

The Director of Cell Therapy Discovery will develop long-term departmental goals aligned with the company's R&D strategy and provide guidance on product development. This role involves leading the design of CAR-T products, managing R&D budgets, and ensuring cross-functional collaboration to meet project milestones.