Downstream Process Scientist at Eurofins

Malvern, Pennsylvania, United States -

Full Time

Start Date

Immediate

Expiry Date

03 Mar, 26

Salary

0.0

Posted On

03 Dec, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Downstream Process Development, Chromatography, Filtration, Data Analysis, Technical Documentation, Team Collaboration, Project Management, Protein Therapeutics, Analytical Method Development, SOP Drafting, Pilot-Scale Operations, Data Integrity, Process Optimization, Technical Transfers, Biologics Manufacture

Industry

Medical and Diagnostic Laboratories

Description

Company Description Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years. Job Description The candidate for this position will work as a member of a small team to perform scale-up/scale-down development of therapeutic biologics with strong emphasis on API proteins within the Large-Scale Development & Operations downstream (DSP) group in Malvern, PA. The candidate’s primary responsibilities will include a component of pilot-scale DSP operations execution, DSP data acquisition and modeling, and optimizing the process steps to be representative of the target process scale to ensure right first time technical transfers. This will include: Pilot-scale and occasional laboratory work with chromatographic purification and several types of filtration systems Record and analyze data, verify data integrity and accuracy, and report/summarize findings to the project development teams Design experiments to optimize DSP operations within the Large-Scale Development & Operations DSP group to ensure that they are representative of internal and external manufacturing sites Draft technical documents, SOPs, and work instructions Work in a team environment as well as contributing individually to meet project timelines and objectives Qualifications Minimum of BS in scientific related discipline is required. Knowledge of and hands-on experience with DSP purification (chromatography, filtration) of protein therapeutics (such as antibodies) is required. Experience with scale-up/down of DSP, and/or execution at pilot or manufacturing scales for biologics manufacture is preferred. Exposure to analytical method development for in-process methods is preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects with some supervision. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is preferred. Data reporting, ability to present findings to management, and experience with team-based collaborations is required. Additional Information Position is full-time, Mon-Fri 9am-5pm. Candidates currently living within a commutable distance of Malvern, PA are encouraged to apply. Excellent full time benefits including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Responsibilities

The candidate will perform scale-up/scale-down development of therapeutic biologics, focusing on API proteins. Responsibilities include pilot-scale DSP operations execution, data acquisition, modeling, and optimizing process steps for technical transfers.