Location Mississauga, Ontario, Canada
Job ID R-233193
Date posted 07/08/2025
The Epidemiology and Real World Science (Epi-RWS) team is a growing group within the Alexion-AstraZenca Rare Disease Unit which is driving the scientific use of Real World Data to accelerate the way that patients access innovative medicines.
The Epidemiologist is a scientific role that involves supporting the development and execution of impactful epidemiological deliverables that deepen our understanding of rare diseases, with a focus on Alexion’s clinical development programs and post-marketing studies.
The role involves working closely with other Epidemiologists and Real World Data Scientists in the department to support the development, execution, interpretation and communication of scientifically robust stage-appropriate evidence that enhances decision-making across the portfolio, such as: conducting literature reviews; characterizing incidence and prevalence to support regulatory and safety documents; critically appraising & synthesizing relevant literature; analysis of real-world databases; describing patient characteristics, natural history, treatment patterns and outcomes; quantification of event rates and phenotypic / genotypic traits or associations; and landscaping for suitable data-sources.
This role involves supporting engagements with colleagues across the company, including: Clinical Development, Global Patient Safety, Regulatory Affairs, Global Medical Affairs, and Global Marketing. The Epidemiologist may participate in cross-functional teams and sub-team meetings, under the guidance of senior members of the Epi-RWS department when appropriate.
The Epidemiologist must have mature team-working behaviors with organizational awareness and insight. The ideal candidate will have experience with analysis and interpretation of epidemiologic data within the context of rare diseases and a passion for applying epidemiology to support life-transforming therapies for patients.

• Supporting the planning, development, and execution of Epidemiology deliverables, with a focus on Alexion’s clinical development programs and post-marketing studies, including: conducting literature reviews, characterizing incidence and prevalence to support regulatory and safety documents; critically appraising & synthesizing relevant literature; analysis of real-world databases; describing patient characteristics, natural history, treatment patterns and outcomes; quantification of event rates and phenotypic / genotypic traits or associations; and landscaping for suitable data-sources.
• Providing epidemiology support into study protocols, analysis plans, and regulatory documents.
• Summarizing results in written reports and oral presentations.
• May participate in cross-functional team meetings and supporting the presentation of summary findings to Alexion internal/external stakeholders.
• Maintaining awareness of epidemiology with respect to regulatory requirements, payer trends, and advancement of pharmacoepidemiology methods.
• Travel may be required (up to 10%).