ERC-funded postdoctoral position focusing on nanobody development for thera at VIB
Gand, , Belgium -
Full Time


Start Date

Immediate

Expiry Date

01 Aug, 25

Salary

0.0

Posted On

02 May, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Phage Display, Characterization, Purification

Industry

Information Technology/IT

Description

Join the Barriers in Inflammation lab led by Roosmarijn Vandenbroucke at the VIB-UGent Center for Inflammation Research (https://vandenbrouckelab.sites.vib.be) for exciting postdoctoral opportunities! Our team of approximately 20 researchers is dedicated to unravelling the underlying causes of CNS disorders, identifying therapeutic targets and assessing their potential for intervention.
We’re offering a postdoctoral position funded by an ERC project aimed at revolutionizing therapeutic delivery into the brain via the blood-CSF barrier. Our pioneering research harnesses the power of single-domain antibodies, also known as nanobodies or VHHs, as a Trojan horse for targeted brain delivery. Our goal is to explore the vast potential of VHHs in effectively transporting diverse cargos -ranging from proteins to nucleic acids and nanoparticles- across the blood-CSF barrier, offering promising solutions for a myriad of neurological disorders. We previously identified a promising candidate that requires further optimization and validation and in addition, we aim to discover novel VHHs capable of crossing the blood-CSF barrier and delivering therapeutic cargoes to the brain.
You will become an integral member of a subteam, working closely with an experienced lab technician, two dedicated PhD students, and two postdoctoral researchers on a project focused on in vitro screening methods, including the use of organoids. We are looking for an individual with expertise in the following specific profiles to enhance and complement the team:

Responsibilities

Please refer the Job description for details

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