Executive Director, Clinical Program Lead at Insmed Incorporated

, New Jersey, United States -

Full Time

Start Date

Immediate

Expiry Date

18 Jul, 26

Salary

417000.0

Posted On

19 Apr, 26

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Clinical development, Clinical strategy, Study design, Safety oversight, Regulatory affairs, Global project management, Medical oversight, Data interpretation, Cross-functional leadership, Strategic planning, Small molecules, Biologics, ICH-GCP compliance, Clinical trial execution, Stakeholder management, Scientific rigor

Industry

Biotechnology Research

Description

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for an Executive Director, Clinical Program Lead (CPL) to help us expand what’s possible for patients with serious diseases. Reporting to the Chief Development Officer, the Executive Director, CPL will provide clinical leadership for Brensocatib across late Phase 2 and Phase 3b development. This role is a core member of the Global Project Team (GPT) and leads the Global Clinical Team, overseeing physicians and clinical scientists responsible for study design, execution, safety oversight, and supporting regulatory engagements. What You'll Do: In this role, you’ll have the opportunity to own and maintain the global Clinical Development Plan (CDP) aligned to the Target Product Profile (TPP) and portfolio strategy. You’ll also: Serve as clinical lead on the cross-functional GPT, accountable for all clinical strategy and deliverables. Embrace the opportunity to support DPP-1 follow-on discussions as those molecules advance. Provide senior medical oversight of global studies, including benefit–risk assessment, safety signal management, and clinical input to regulatory interactions (FDA, EMA, PMDA). Lead the design of mid-to-late-stage clinical trials ensuring compliance with ICH-GCP, ethical standards and global regulatory requirements. Build, lead, and develop a high-performing global clinical team of physicians and scientists to support current and future Brensocatib programs. Establish and maintain strategic relationships with key external experts, investigators, and advisors supporting the development program. Who You Are: You must have an MD and 10+ years of clinical development experience in biotech or pharma, with late-stage program leadership across small molecules and biologics. Additionally, you have: Demonstrated leadership of global Phase 2–3b programs, including clinical strategy, execution, and data interpretation. Strong knowledge of global regulatory pathways and interactions (FDA, EMA, PMDA). Proven ability to lead and influence in complex, matrixed, cross-functional organizations. Exceptional written and verbal communication skills with scientific, regulatory, and executive stakeholders. Strategic clinical judgment and scientific rigor. Ability to influence and act decisively within matrixed environments. Executive-level communication and external presence. Ability to navigate ambiguity and drive timely, high-quality decisions. Commitment to patient safety, data integrity, and ethical standards. Nice to have (but not required): Board certification in Pulmonary or Allergy strongly preferred. Combination drug-device experience focusing on respiratory diseases strongly preferred. PhD in addition to the MD above. Where You’ll Work This is a hybrid role based out of our Bridgewater, NJ office. You’ll have the option to work remotely most of the time, with in-person collaboration when it matters most. Travel Requirements This role requires occasional domestic or international travel (approximately 20%). #LI-MM1 #LI-Hybrid Pay Range: $306,000.00-417,000.00 Annual Life at Insmed At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself. Highlights of our U.S. offerings include: Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP) Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. Current Insmed Employees: Please apply via the Jobs Hub in Workday. Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address. Applications are accepted for 5 calendar days from the date posted or until the position is filled. For New York City Residents: To assist in identifying candidates with qualifications matching those required and/or preferred for this role, Insmed uses an Automated Employment Decision Tool (“AEDT”) that employs artificial intelligence to analyze and score information provided in resumes and application materials including, but not limited to, skills, work experience, education, and job-related qualifications. The AEDT does not make final hiring decisions and all final hiring decisions are subject to human oversight and/or review. If you are an applicant for this role and a New York City resident, you have the right to request: A reasonable accommodation, if one is available under applicable law, by emailing TotalRewards@insmed.com; and/or An alternative selection process by emailing Privacy@insmed.com. Information about the type of data collected, the source of that data, and data retention practices related to the AEDT by emailing us at Privacy@insmed.com. Insmed is a people-first global biopharmaceutical company driven to transforming the lives of patients with serious and rare diseases. Headquartered in Bridgewater, NJ, with locations across the U.S., EMEA, and Japan, we’re guided by our core values and a shared commitment to patients and each other. We’ve been named Science’s No. 1 Top Employer four years in a row, certified as a Great Place to Work in the U.S., and recognized among The Sunday Times’ and BioSpace’s Best Places to Work. For patients, each other, and the future of science, we’re in. Are you? Wherever you are in the world or in your career, we want to stay connected. Sign up for our talent community to hear about new career opportunities, company news, and how our teams around the world are striving to make a difference for patients every day. Sign UP

Responsibilities

The Executive Director, Clinical Program Lead will provide clinical leadership for Brensocatib, overseeing study design, execution, and safety oversight. They will lead the Global Clinical Team and serve as a core member of the Global Project Team to ensure alignment with the global Clinical Development Plan.