Executive Director, Program at Seaport Therapeutics

Boston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

03 Jun, 26

Salary

310000.0

Posted On

05 Mar, 26

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Program Leadership, Cross-functional Leadership, Drug Development, Pre-commercialization, Strategic Planning, Risk Mitigation, Stakeholder Alignment, Regulatory Filings, Market Research, Team Management, Conflict Management, KOL Relationships, Budget Management, Timeline Management, Data Integration, Problem Solving

Industry

Biotechnology Research

Description

Seaport Therapeutics is a clinical-stage biopharmaceutical company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders. For more information, please visit www.seaporttx.com. Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders. For more information, please visit www.seaporttx.com. Seaport Therapeutics is seeking a talented and experienced Program Leader (PL) to be an integrative cross-functional leader who is responsible for driving the GlyphAllo Program in order to maximize its future clinical and commercial success in the treatment of depression. This is a highly visible leadership role that bridges scientific, clinical, operational, and commercial disciplines. The GlyphAllo program is currently enrolling a Phase 2b study and the PL will lead the program to execute the current plans within timelines/budget and to plan for future pivotal clinical studies, initial global regulatory filings and pre-commercial activities. He/she will provide leadership across the spectrum of drug development and pre-commercialization activities, ensuring achievement of program and corporate goals. The ideal candidate will be a strategic and entrepreneurial leader well-versed in drug development and commercialization, and a strong influencer who can integrate multiple perspectives effectively and align stakeholders across different functions and levels of the organization. This position requires a presence in the Seaport area of Boston, with a strong preference for being onsite 4 days per week to foster collaboration and effective leadership as the GlyphAllo program grows in complexity and importance. The role will report to the Chief Operating Officer (COO), with strong working relationships with the entire Executive Leadership Team (ELT). Summary of Key Responsibilities · Serve as the overall program lead, accountable for end-to-end planning, execution, and delivery of key milestones of clinical studies through NDA submission. · Work collaboratively and cross-functionally with Research, Nonclinical Development, Clinical Operations, Clinical Research, Regulatory Affairs, Medical Affairs, Manufacturing, Quality Assurance, Drug Safety & Pharmacovigilance, Program Management, Distribution & Supply, Commercial and Finance to deliver on program goals within established timelines and budget. · Partner closely with Program Management to drive alignment and execution across the cross-functional program team, including development and maintenance of integrated, cross-functional strategic plans, timelines, and budgets; proactive identification of risks; and implementation of mitigation strategies. · Oversee the development of market research plans to gather deep insights from patients, providers, payers, and other stakeholders. Integrate the insights and other market competitive intelligence into program strategies. · Integrate cross-functional perspectives, ensuring that program strategy is informed by scientific evidence, clinical data, and the evolving competitive landscape. On an ongoing basis, proactively anticipate issues and ensure contingency plans are put in place; identify barriers and identify solutions to mitigate them; identify opportunities and strategies to capitalize on them. · Working with functional leaders, ensure that appropriate prioritization and adequate resource allocation (financial and personnel) are present to meet the program timelines and deliverables. · Maintain a high performing cross-functional program team, monitoring program resourcing, managing conflict, and building team culture; create a positive atmosphere to get the most out of the team. · Serve as an internal and external ambassador for the program, fostering broad engagement to cultivate strategic KOL relationships and enabling overall integration of external insights to inform program strategies. · Summarize and represent the program to Seaport leadership, Board of Directors, collaborators, and other external parties, as requested. Qualifications · BA/BS degree required; advanced medical, scientific or business degree strongly preferred. · 10+ years biopharmaceutical development and commercialization experience, with previous demonstrated program leadership responsibilities; demonstrated experience leading cross-functional teams in drug development and pre-commercialization. · Deep understanding of drug development and global product registration is required, ideally in neuropsychiatry (with preference for experience in depression or anxiety). Commercialization and /or Medical Affairs experience considered a strong plus. Leadership of a recent successful program (positive pivotal data, regulatory approval, etc.) would be ideal. · Proactive “hands-on” individual with collaborative orientation, who manages teams effectively, is very self-motivated and can smoothly establish strong working relationships within both internal and external organizations. Entrepreneurial problem solver. Achieves goals within timelines and budgets while anticipating and navigating obstacles effectively. · Initiative and independence to identify short and long-term program needs, creatively formulate plans with team input, efficiently achieve timely decisions/alignment, and organize and deploy resources. · Exceptional written and verbal communication skills; able to articulate program vision and motivate the team; communicates in an open, direct and timely manner; ensures broader organization is aligned with and aware of the program strategy, status and risks. · Motivated by patient focus and personal commitment to high performance and results. · Possesses high integrity and exceptional work ethic. At Seaport, we believe transparency and fairness are key to building a culture of trust, respect, and collaboration. We care deeply about the happiness of our team and strive to ensure our total rewards (monetary and non-monetary) program reflects the value each person brings. The expected salary range for this role is $275,000-310,000 with the final offer based on experience, market data, and internal equity. We encourage open conversations with our talent acquisition team about compensation early in the process to ensure alignment from the start.

Responsibilities

The Executive Director, Program will serve as the overall program lead, accountable for end-to-end planning, execution, and delivery of key milestones for the GlyphAllo Program through NDA submission. This involves working cross-functionally to drive strategic plans, manage risks, oversee market research, and ensure appropriate resource allocation to meet program goals within timelines and budget.