Expert Science & Technology - Synthesis Technician at Novartis

Basel, Basel-City, Switzerland -

Full Time

Start Date

Immediate

Expiry Date

29 Jul, 26

Salary

0.0

Posted On

30 Apr, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Chemical synthesis, Process development, Bioconjugation, Antibody-oligonucleotide constructs, Laboratory operations, Analytical data generation, SEC chromatography, Chromeleon, Documentation, Small molecule drug substances, Chemical modification, Fermentation products, Quality control, Process manufacturing

Industry

Pharmaceutical Manufacturing

Description

Job Description Summary Location: Basel, Switzerland #onsite Role Purpose: As a global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented, performance driven people. All of which makes us one of the most rewarding employers in our field. The position is within the Global Technical R&D department of Novartis Global Drug Development. Chemical & Analytical Development (CHAD) plays an essential role in the development of processes for manufacturing and analysis of complex small molecule drug substances from the time it leaves the discovery laboratory until it is handed over to Commercial Production. In this position you will play an important role in developing chemical synthetic processes for the manufacture of our future drugs substances with a focus on bio-conjugation products. Antibody-Oligonucleotide constructs will be the core focus of the position. Job Description Major accountabilities: With your strong expertise and skill in laboratory operations, you take an important role in defining future manufacturing processes and strategies for bioconjugation projects such as Antibody-Oligonucleotides. In our labs, you will generate essential synthetic and partly analytical data to evaluate and define the manufacturing processes for bioconjugations providing best possible quality, efficiency and environmental compatibility As a member of drug substance team, you collaborate closely with our internal and external partners to ensure timely and quality delivery of new oligonucleotide drugs to our patients Further, he/she provides relevant documentation of experiments and related information in support of filing and patents He/she also actively maintains and optimizes our lab infrastructure ensuring safe and efficient execution of chemical experiments Minimum Requirements: Education: Minimum requirement is successful completion of a relevant apprenticeship (e.g. Laborant Chemie/ Analytik EFZ or equivalent). Position is also open to applicants with completed BSc. or MSc. Experience: In addition the ideal candidate would have the following professional experience: 3-5 years experience in synthesis/ chemical process development is a strong requirement Proven knowledge in space of bioconjugation or chemical modification of fermentation products, e.g. Antibody-Drug Conjugations or other complex molecular structures is desirable Advanced knowledge of software and computer tools such as Office package, chromatography data-evaluation software (e.g. Chromeleon) is desirable Experience in use of SEC chromatography or other relevant analytical techniques is also a benefit Independent and self-motivated workstyle with team orientation and adequate communication style Good documentation skills required during execution of experiments and documentation of results Languages : Adequate knowledge of English language is required (oral and written), German and other language skills are beneficial. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Skills Desired Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives. Novartis is aware of employment scams which make false use of our company name or leader’s names or recruiter’s names to defraud job seekers. Novartis does not make job offers without interview and never asks candidates for money. If you have encountered a job posting or been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond, send money or personal information. In the context of China Cross-Border Data Transfer (CBDT) policy, if you need to apply for a position in China, please go to the local Recruiting System TaleNov .

Responsibilities

You will develop chemical synthetic processes for manufacturing complex drug substances, specifically focusing on antibody-oligonucleotide constructs. Additionally, you will generate analytical data and maintain laboratory infrastructure to ensure safe and efficient experimental execution.