High-throughput ADME Screening Group Lead at Eli Lilly
Louisville, Colorado, USA -
Full Time


Start Date

Immediate

Expiry Date

12 Sep, 25

Salary

294800.0

Posted On

13 Jun, 25

Experience

10 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Liquid Handling, Mass Spectrometry, Automation Tools

Industry

Information Technology/IT

Description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
The Investigative ADME/Toxicology and BioAnalytical Research (BAR) group is an organization purpose-built team to ensure we provide stage-appropriate, problem-focused to molecular creation teams that make life better for people. We focus on using innovative science to unlock new approaches that can treat people suffering from diseases with poor treatment options. We continually challenge ourselves to deliver molecules that can provide breakthrough efficacy with the highest possible safety margins. We are committed to continually optimizing our approach, technology and processes to improve our speed of execution. We relentlessly pursue a culture anchored in empowering scientists and teams to innovate and advance projects through deep collaboration and personal accountability.

POSITION SUMMARY:

The Investigative ADME/Toxicology and BioAnalytical Research team focuses primarily on drug discovery using both traditional and novel scientific approaches. We seek an experienced leader for our cross-site ADME Screening team. The candidate should have a passion for developing capacity enabling early tier screening assays which deliver reliable results at the pace discovery research demands. The candidate should demonstrate a record or leading groups across multiple sites while maintaining a deep knowledge of current technology to solve draggability challenges across modalities. Collaboration with ADME project leaders, lab-based scientists and medicinal chemists is essential. This role requires excellent people skills, a positive attitude, willingness to learn, attention to detail, and the ability to thrive in a fast-paced team environment.

Basic Requirements:

  • PhD with minimum of 10+ years academic/research/industry exp (may include post-doc experience), MS with 15+ years industry/academic/research exp, or BS with 20+ years industry/academic/research experience within the pharmaceutical sector, or a closely related field.
  • Demonstrated experience with key technologies, including automated liquid handling, high speed liquid chromatography–tandem mass spectrometry (LC-MS/MS) for sample analysis, and software and automation tools to support the throughput and capacity required for early phases discovery assay support
Responsibilities
  • Lead a cross-site team of Screening ADME scientists, primarily focused on the support of the new Lilly Small Molecule Discovery (LSMD) group, but one that can also provide support to LRL therapeutic areas and molecular creation teams (LGM, and BioTDR).
  • Establish a stage-oriented, high-capacity screening team focused on cross-site integration, execution and organizational effectiveness for team members primarily in Indianapolis and Colorado.
  • Ensure on-demand, problem-focused screening is accomplished in support of programs in discovery and amplify project takeaways to improve performance primarily within discovery.
  • Work with other leaders across the Investigative ADME/Toxicology and BioAnalytical Research organization to ensure critical success factors are outlined for teams, while working to provide prompt delivery which will include assay development, data analysis and reporting.
  • Provide guidance and next-level mentorship to members of the Screening ADME team.
  • Champion an environment that challenges the organization to actively tackle challenging problems, while evaluating/internalizing new technology to increase efficiency and excellence to the group.

Basic Requirements:

  • PhD with minimum of 10+ years academic/research/industry exp (may include post-doc experience), MS with 15+ years industry/academic/research exp, or BS with 20+ years industry/academic/research experience within the pharmaceutical sector, or a closely related field.
  • Demonstrated experience with key technologies, including automated liquid handling, high speed liquid chromatography–tandem mass spectrometry (LC-MS/MS) for sample analysis, and software and automation tools to support the throughput and capacity required for early phases discovery assay support.
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