Interaction Analytics (Level: Senior Research Associate to Scientist) at Ridgeline Discovery

Basel, Basel-City, Switzerland -

Full Time

Start Date

Immediate

Expiry Date

09 Sep, 26

Salary

0.0

Posted On

11 Jun, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Biolayer Interferometry, Surface Plasmon Resonance, Kinetics Exclusion Assays, ELISA, MSD, FACS, Protein Engineering, Recombinant Protein Characterization, Antibody Discovery, Epitope Binning, Binding Kinetics, Drug Discovery

Industry

Biotechnology Research

Description

About us Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale. Responsibilities You will further strengthen our team by supporting the development of new biotech programs. In this role, you will contribute to the characterization of recombinant proteins (e.g., antibodies, antibody conjugates, and small molecules) by applying state‑of‑the‑art techniques to: Determine affinity and binding kinetics on recombinant proteins Assess interaction specificity Conduct epitope binning experiments Interact with and support the coordination of external providers Support the design, optimization, and characterization protein variants for e.g., extracellular receptor domains, antibodies and, antibody fragments Ensure careful documentation and support the interpretation of experimental results Conribute to the preparation of reports, including IND-related documentation when required Present results in internal meetings and support external presentations as needed Evaluate and help implement new protein interaction assays and technologies Qualifications You are a highly motivated and independent individual with excellent communication and interpersonal skills, and you enjoy working collaboratively in a diverse team environment. You hold a degree in biotechnology, biochemistry, biology, or a related field or have completed vocational training as laboratory assistant (e.g., BTA, MTA or CTA), or have a comparable qualification. In addition, you bring: At least 3 years of hands-on experience with biosensor instruments such as biolayer interferometry (BLI), surface plasmon resonance (SPR) and/or kinetics exclusion assays (KinExA) Expertise in the characterization of antibodies and other recombinant proteins using techniques such as ELISA, MSD and, FACS Solid understanding of the design and evaluation of interaction studies, with the ability to independently plan and conduct experiments Experience in protein engineering, with an understanding of hit-to-lead discovery processes in drug discovery Good command of English, both written and spoken What we currently offer People: We are an international and diverse team with talented and passionate people. Creativity: We offer an innovative and creative environment. Development: We support the individual development of our employees. Fun: From time-to-time we organise cool off-site summer and winter team events. Offices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel. Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution. Flexible Working: We support flexible working as appropriate. Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year. Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off. Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge. Please note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement.

Responsibilities

The role involves characterizing recombinant proteins and antibodies using state-of-the-art biosensor techniques to determine affinity and binding kinetics. You will also support the design of protein variants and contribute to IND-related documentation and internal reports.