Intern, Neuroimmunology (BS/MS) at Calico

South San Francisco, California, United States -

Full Time

Start Date

Immediate

Expiry Date

06 Mar, 26

Salary

70.0

Posted On

06 Dec, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Cell Biology, Neuroscience, Immunology, Teamwork, Communication, Tissue Culture, Microscopy Techniques, Functional Genomics, CRISPR, Single-Cell Transcriptomics, Protein Binding, Laboratory Animal Work, Data Analysis, Cell Tracking, In Vitro Assays, In Vivo Assays

Industry

Biotechnology Research

Description

Position description: Calico is seeking an intern to join the Hahn group in their mission to investigate the mechanisms driving brain aging and age-related neuroinflammation. To succeed, you will need to be an enthusiastic team player, detail-oriented, extremely organized and comfortable working on complex problems. In this position you will support our efforts to harness novel screening systems (like this) to study brain immune cells at scale, in order to identify novel regulators of their cellular physiology. The successful candidate will work closely with members of the Hahn group on combining novel and innovative primary and progenitor-derived cell culture systems with advanced functional assays and in vivo cell tracking approaches, with the long-term aim of uncovering novel biological drivers of immune aging. Responsibilities: Prepare, optimize and run in vitro and/or ex vivo cell phenotyping assays Analyze multiplexed image-based data Work in collaboration with other members of the group on ex and in vivo cell tracking methods Position requirements: Currently pursuing a BS or MS degree in cell biology, neuroscience, immunology, or related field Interest in brain physiology and age-related changes Detail-oriented and organized Strong teamwork and communication skills Self-motivated with a “can-do” attitude Ability to work on-site in the South San Francisco lab space Technical requirements (one or more of the following): Hands-on experience with tissue culture/sterile techniques Hands-on experience and comfortable with laboratory animal work Hands-on knowledge of microscopy techniques for imaging fixed and/or live tissue Nice to have: Experience with analysis of microscopy-based imaging and/or single-cell transcriptomics data Experience with functional genomics/CRISPR/single gene knockouts About our Program: Calico’s internship program is a paid 12-week program over the summer for students interested in understanding the fundamental science of aging and finding treatments for the associated and intractable diseases. Working in a collaborative environment and fully embedded in one of our labs/teams, Calico interns tackle a unique project under the mentorship of at least one of our scientists or engineers. Program Features: 3-month summer timeline In-person experience at our offices in South San Francisco Matching with at least one Calico mentor Group supplemental activities weekly featuring guest speakers, Senior Leadership spotlights, and discussion groups on aging science, our drug development approach, and more End-of-summer company-wide project showcase and poster session Competitive compensation ($45 - $70/hour) and monthly living expenses stipend Nice to have: Familiarity with experimental structural biology techniques Prior experience with protein binding or functional assays would be helpful as would experience using an electronic notebook (such as Benchling), online registries (UniProt, NCBI, Protein Data Bank), and using software to design DNA plasmids (SnapGene) and to analyze protein structures (PyMol or ChimeraX) Program Eligibility: Able to work in-person at our offices in South San Francisco Free for a consecutive period of 11-12 weeks in June, July, and August Not graduating before December 2026 Exception for students enrolling into a graduate degree program in Fall 2026 Must be enrolled in a US university Must apply by application deadline: February 1, 2026.

Responsibilities

The intern will prepare, optimize, and run in vitro and/or ex vivo cell phenotyping assays, and analyze multiplexed image-based data. They will also collaborate with other group members on ex and in vivo cell tracking methods.