Intern, Translational Research (Project: Fc-mediated receptor functions in at Genmab
Utrecht, Utrecht, Netherlands -
Full Time


Start Date

Immediate

Expiry Date

06 Aug, 25

Salary

0.0

Posted On

07 May, 25

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Data Analysis, Life Sciences, Graphpad Prism, Biomedical Sciences, Excel, Cell Biology, Cdc, Flowjo, Immunology, Cell Culture, Training, English

Industry

Information Technology/IT

Description

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.
Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.
Does this inspire you and feel like a fit? Then we would love to have you join us!

WHY GENMAB

Our internship program provides interns with hands-on experience and relevant projects that directly align with our company’s goals. Additionally, we believe our program provides a valuable opportunity to learn, thrive, and build a strong network. We encourage you to review our website to learn why we’re always looking for smart, purpose-led candidates to play a role in our bold, extra[not]ordinary® future.

REQUIREMENTS

  • Currently enrolled in a Bachelor HBO Life Sciences or Master’s degree program at a Dutch university in Biomedical Sciences, or a related field.
  • Available for a minimum of 6 months (up to 12 months).
  • Basic knowledge of immunology, cell biology, and antibody-based therapeutics
  • Prior laboratory experience with cell culture and standard cellular techniques is an asset
  • Capable of performing data analysis and interpretation, with a strong focus on delivering accurate, reliable, and meaningful research findings
  • Ability to work independently and collaboratively within a multidisciplinary team

PREFERRED QUALIFICATIONS, CAPABILITIES, AND SKILLS

  • A motivated and curious individual who thrives in collaborative research environments
  • Open to feedback and eager to learn new techniques or concepts as needed for the project
  • Strong organizational skills and attention to detail.
  • Demonstrated ability to manage time effectively and prioritize tasks in a fast-paced research environment
  • Familiarity with in vitro assay workflows, including functional assays like ADCC, ADCP, or CDC is a plus (training can be provided).
  • Knowledge of data analysis tools such as Excel, GraphPad Prism, or FlowJo is valued.
  • Fluency in English, with the ability to communicate scientific concepts clearly and effectively.
Responsibilities

THE ROLE

Are you excited about cancer immunology, looking to make a meaningful impact in the field of antibody therapeutics? Do you want to gain exposure to the strategic design of innovative antibody therapeutics? Keep on reading!
We are seeking a highly motivated intern to join one of our Expertise Teams within the Translational Research department. In this lab-based role, you will play an active part in advancing preclinical research for novel antibody therapeutics. Working under the direct supervision of the Expertise Team Lead and a project scientist, you will contribute meaningfully to the development and execution of our preclinical research strategy.
Monoclonal antibodies (mAbs) are a major therapeutic modality for many cancer patients, owing to their ability to selectively target tumor-associated antigens. Beyond direct tumor cell binding, mAbs exert immune-mediated effects through their constant Fc regions, which engage immune effector cells and activate the complement system. These Fc-mediated effector functions include antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC).

RESPONSIBILITIES

You will apply a range of advanced in vitro techniques including cell culture, flow cytometry, live-cell imaging, and functional cellular assays such as ADCC, ADCP, and CDC to investigate these Fc-driven mechanisms in solid tumor models, with a particular focus on understanding how complement influences the modulation and amplification of Fc effector functions.

  • With the help of your mentor, you will manage the design, planning, and execution of experiments for assigned research studies.
  • Support the research strategy by proposing and designing follow-up experiments informed by emerging data and current literature.
  • Stay curious and open to learning new assays, techniques, and analysis methods while approaching challenges with a solutions-driven mindset.
  • Document, process, and analyze experimental results promptly. Draw meaningful conclusions, contextualize findings, and present insights to the team.
Loading...