THE POSITION

Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 45 years.
Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

WHO YOU ARE

We are seeking a strategic leader with a strong background in manufacturing execution systems (MES), digital transformation, and change management. You are highly skilled at navigating complex, global organizations, leading cross-functional teams, and driving large-scale strategic initiatives to completion.
You possess business acumen in the pharmaceutical sector, with the ability to synthesize information, manage competing priorities, and align multiple stakeholders to a shared vision.

Key Qualifications & Competencies:

• Master’s Degree in Engineering, Business, or related field with 8+ years of experience in Life Sciences, pharmaceuticals, or regulated industries.
• Proven leadership and decision-making abilities in driving large-scale strategic initiatives.
• Strong understanding of MES solutions and digital enablement in manufacturing processes.
• Experience working in matrix organizations, collaborating across diverse teams.
• Excellent stakeholder management, negotiation, and communication skills.
• Knowledge of global regulatory requirements.
• Ability to drive process harmonization, optimization, and continuous improvement.
• Comfort working in a dynamic, evolving environment and influencing senior stakeholders.
• Willingness to travel globally as required.

THE EXPECTED SALARY RANGE FOR THIS POSITION BASED ON THE PRIMARY LOCATION OF SAN FRANCISCO, CA IS $156,500 - $290,700 . ACTUAL PAY WILL BE DETERMINED BASED ON EXPERIENCE, QUALIFICATIONS, GEOGRAPHIC LOCATION, AND OTHER JOB-RELATED FACTORS PERMITTED BY LAW. A DISCRETIONARY ANNUAL BONUS MAY BE AVAILABLE BASED ON INDIVIDUAL AND COMPANY PERFORMANCE. THIS POSITION ALSO QUALIFIES FOR THE BENEFITS DETAILED AT THE LINK PROVIDED BELOW.

Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

WHAT YOU’LL DO

Strategic Leadership & Execution

• Lead the execution of strategic MES initiatives, ensuring alignment with business priorities and PT network goals.
• Collaborate with MES Business Process Owners (BPOs), site MES leaders, and third-party software owners to harmonize MES business processes and drive successful program implementation.
• Translate strategic objectives into actionable initiatives and oversee their implementation across multiple manufacturing sites.
• Ensure that all MES initiatives align with the Core MES Model, industry best practices, and regulatory requirements.

Cross-Functional Collaboration & Stakeholder Management

• Work with a global matrix team of BPOs, IT/OT teams, IIX, site leadership, and external software providers to drive cross-functional execution of MES initiatives.
• Establish and maintain effective stakeholder engagement, ensuring alignment, transparency, and collaboration across diverse teams.
• Facilitate decision-making forums to ensure MES strategies are executed effectively and key roadblocks are addressed proactively.
• Partner with IT and business teams to ensure seamless integration of MES with enterprise platforms and digital transformation initiatives.

Change Management & Communication

• Drive organizational change management strategies to support MES adoption, including training, communication plans, and user engagement.
• Develop effective communication frameworks to keep stakeholders informed on MES program progress, key milestones, and implementation timelines.
• Act as a change advocate, ensuring best practices and lessons learned are shared across the PT network.

Process Optimization & Continuous Improvement

• Work with the global BPO to Identify, analyze, and drive improvements in MES implementation processes to enhance efficiency, compliance, and effectiveness.
• Establish and track key performance indicators (KPIs) to measure the success of MES strategic initiatives.
• Lead continuous improvement efforts to optimize MES workflows and business processes across sites.

Governance & Compliance

• Ensure MES strategic initiatives are executed in compliance with Roche GSP and Heath Authority requirements.
• Contribute to the development of governance structures that maintain consistency, quality, and adherence to industry standards.