Start Date
Immediate
Expiry Date
02 Nov, 25
Salary
2.901
Posted On
03 Aug, 25
Experience
4 year(s) or above
Remote Job
Yes
Telecommute
Yes
Sponsor Visa
No
Skills
Good communication skills
Industry
Education Management
Vacancy number
15913
Job type
Academic staff, PhD positions
Hours (in fte)
1,0
External/ internal
External
Location
Leiden
Placed on
1 August 2025
Closing date
1 November 2025 92 more days to apply
PHD CANDIDATE IN IMMUNO-BIOLOGY AND INFECTIOUS DISEASE
The Faculty of Science Leiden, the Leiden Institute of Biology and Leiden Institute of Chemistry are looking for a PhD candidate to pursue research on the development of host-directed therapeutics for mycobacterial infections.
Mycobacterial infections are among the top 10 cause of death globally. Although cases of tuberculosis (Mtb) are typically decreasing because of concerted global efforts, respiratory infections cause by non-tuberculous mycobacteria (NTM), such as M. avium, have more than doubled since the year 2000. The increase in antibiotic resistance is a major concern for both Mtb and NTM, and there is need for novel therapeutics. This PhD project investigates the potential of targeting host-cell metabolism to deprive intracellular bacteria of essential nutrients and boost the immune response. The candidate will work as part of an interdisciplinary team to help characterize how pathogenic mycobacteria rewire host-cell metabolism and identify novel drug targets. They will be trained in a variety of powerful, modern analytic techniques including metabolomics, transcriptomics, and proteomics and work on advanced biological systems for modelling infection including macrophages, organoids, zebrafish, primary and clinical samples.
Embedding within the Institutes of Biology and Chemistry at Leiden will enable the candidate to maximize their learning opportunities, participate in local research networks, and access leading research facilities.
DESCRIPTION OF ORGANISATION AND TERMS OF EMPLOYMENT
The position is open and will commence as soon as a suitable candidate is admitted. We offer a position for 12 months and upon satisfactory performance to be extended for three more years. You will be appointed in accordance with the Collective Labour Agreement for Dutch Universities. The salary ranges from € 2.901,- to € 3.707,- gross per month (pay scale P in accordance with the Collective Labour Agreement for Dutch Universities).
Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information, see the website.
UNIVERSITY
Leiden University is one of Europe’s leading international research universities.
Thanks to its committed and inspired employees, the university enjoys a leading role in academic research and education. Leiden also scores very well every year in prominent rankings. This means that, to maintain our position, the bar is set very high. Regardless of the work you do at our university, you are always encouraged to broaden your horizons, develop your talents and reach your full potential. Will you become our newest colleague?
If you have questions about you eligibility or other administrative questions, please contact Jessica van Krimpen (j.e.van.krimpen@lic.leidenuniv.nl), or review the graduate student webpages.
You can find more information about the faculty of Science at https://www.universiteitleiden.nl/en/science/about-faculty-of-science. For more information about working at Leiden university please visit https://www.universiteitleiden.nl/en/working-at.
Are you enthusiastic about this vacancy? We are looking forward to getting to know you.
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