The University of Florida, Department of Cellular and Systems Pharmacology is seeking to hire a Post Doctoral Associate in the lab of Dr. Anutosh Chakraborty.
Research focus of the Chakraborty laboratory: Obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) are significant health concerns. A complete knowledge of the mechanisms that cause these diseases is lacking, which hinders the development of safer therapeutic strategies for their treatment. The Chakraborty lab aims to understand mechanisms that regulate the development and progression of these diseases. Using novel, lab-generated mouse models, and available human patient samples, the lab identifies and validates novel targets in obesity and MASLD and subsequently develops pharmacological tools that ameliorate these diseases by targeting these proteins. The lab uses diverse techniques such as proteomics, transcriptomics, lipidomics and cell and molecular biology and pharmacology in cell lines, primary cells and mouse models of obesity and MASLD. Prior work from the lab discovered the inositol hexakisphosphate kinase-1 (IP6K1) and the E3 ubiquitin ligase Ube4A as novel targets in obesity and MASLD (Cell, 2010; JCI, 2016; Mol. Metab., 2016; Biol Rev Camb Philos Soc. 2018; Mol. Metab. 2021; J. Med. Chem., 2022; Biomolecules, 2023; Mol. Metab. 2023).
Job description: The Postdoc will be responsible for designing and conducting in vitro and in vivo metabolic experiments in models of obesity and MASLD with minimum guidance from the PI. He/she will independently obtain, store and organize data and generate figures and write methodologies for manuscripts and grant applications, present the data at the lab meetings and conferences and mentor undergraduate and graduate students in the lab. He/she is also expected to collaborate in and outside the lab.
Chakraborty lab publications: https://pubmed.ncbi.nlm.nih.gov/?term=anutosh+chakraborty&sort=date
Chakraborty lab webpage: https://pharmacy.ufl.edu/profile/chakraborty-anutosh/

REQUIRED QUALIFICATIONS:

Candidates must have a Ph.D. in biomedical sciences, encompassing but not restricted to Pharmacology and Physiology; having the necessary skills in the areas of drug discovery, cellular and in vivo assays and mouse models of obesity and MASLD. Experience in isolating primary hepatocytes is required.

Please refer the Job description for details