Postdoc in Experimental Toxicology - DTU Food at Danmarks Tekniske Universitet

Kongens Lyngby, Capital Region of Denmark, Denmark -

Full Time

Start Date

Immediate

Expiry Date

22 Apr, 26

Salary

0.0

Posted On

22 Jan, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Experimental Work, Molecular Characterization, Histopathological Characterization, Large-Scale Expression Analyses, Ex Vivo Culture Models, Primary Cell Models, Stem Cell Models, RNAseq, PCR, Histological Stainings, Independent Research, Data Presentation, Supervision, Teaching, Risk Assessment, Collaboration

Industry

Research Services

Description

We are seeking a highly motivated and dedicated researcher for a 2 year and 6 months postdoctoral position in the field of molecular and experimental toxicology. This position offers an exciting opportunity to contribute to cutting-edge research that addresses one of the most pressing challenges in regulatory toxicology today: identifying endocrine-disrupting chemicals (EDCs) using innovative methodologies that reduce reliance on traditional animal-based testing. This position is part of our efforts to develop New Approach Methodologies (NAMs), which align with global trends toward more ethical, efficient, and predictive testing strategies for chemical risk assessment. The primary focus of this research is on developing models for thyroid hormone system disruption. We know from epidemiological studies that disruption of this hormone system during pregnancy can lead to a range of associated effects such as reduced IQ and behavioral changes in the child. Despite the severity of these effects, few NAMs have been validated under the OECD to screen chemicals for thyroid hormone system disruption and few models for chemical testing have been described that can synthesize thyroid hormones. The project focusses on developing such models. You will work on advancing the science of endocrine disruption by applying a multidisciplinary approach that integrates experimental work with regulatory science. The goal is to enhance our capacity to predict endocrine activity and related toxicity in a manner that supports regulatory decision-making. As part of this project, you will utilize a variety of experimental techniques and approaches, including but not limited to molecular and histopathological characterization of tissues, organs, and cells, large-scale expression analyses, use and development of ex vivo culture models, primary cell models and stem cell models. Beyond experimental work, you will also play a key role in an in vitro model validation project. Your contributions will involve daily management and evaluation of results. You will be part of the Molecular & Reproductive Toxicology research group at DTU National Food Institute, which works at the intersection of basic research and applied science. The group has a strong focus on early-life chemical exposure, endocrine disruption, and reproductive health. You will join a dynamic and supportive research environment that values collaboration, creativity, and excellence. Aligned with the group’s advisory tasks (chemical assessments), you will also be expected to contribute to this work Responsibilities and qualifications This position is primarily research-focused but also involves teaching and providing expert advisory support in the hazard and risk assessment of chemicals with suspected endocrine-disrupting properties. The role requires a highly motivated, adaptable individual with strong organizational skills. Collaborative skills are essential, as you will contribute to several large-scale projects and play a central role in coordinating diverse aspects of project collaborations within the group and internationally. Additional responsibilities include: Carry out experimental work, including use and development of ex vivo culture models, primary cell models from different species, and models based on human induced pluripotent stem cells applying methods such as RNAscope, RNA seq, PCR, histological stainings (IHC/IF). Conduct independent research projects, from initial conception and design through to completion. Communicate research results: presenting data at national and international conferences and meetings, writing reports and manuscripts for publication. Supervise BSc and/or MSc student. Potentially PhD student(s). Contribute with teaching in educational course(s). Support senior risk assessors with research-based advice for Danish authorities. Having prior experience with some, or all, of the listed responsibilities will be viewed favourably. As a formal qualification, you must hold a PhD degree (or equivalent). We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 2 years and 6 months. You can read more about career paths at DTU here. Further information Further information may be obtained from Professor and Head of Research Group, Terje Svingen at tesv@food.dtu.dk You can read more about DTU National Food Institute at www.food.dtu.dk/english and the research group at https://www.food.dtu.dk/english/Research/Molecular-and-Reproductive-Toxicology If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Application procedure Your complete online application must be submitted no later than 11 February 2026 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include: Application (cover letter) CV Academic Diplomas (MSc/PhD – in English) List of publications Applications received after the deadline will not be considered. All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position. DTU National Food Institute DTU National Food Institute conducts research into and disseminates - through advice, innovation and teaching - sustainable and value-creating solutions in the area of food and health for the benefit of society. The vision is to make a difference by generating future prosperity through research into food and health. The institute works to prevent disease and promote health, develop new and better food products for a growing population and create sustainable technological solutions, including biosolutions. The institute’s tasks are carried out in interdisciplinary collaboration within e.g. nutrition, chemistry, toxicology, microbiology, epidemiology, modelling, and technology. This is achieved through a strong academic environment of international top class with correspondingly skilled researchers and employees. The Institute employs approximately 375 staff members. Technology for people DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Responsibilities

The researcher will carry out experimental work and conduct independent research projects related to endocrine disruption and chemical testing. They will also communicate research results and supervise students.