We are looking for a highly skilled and motivated postdoctoral researcher to work on deciphering the molecular mechanisms of how eukaryotic cells construct cilia organelles through selective recognition and trafficking of cargo proteins. The project will utilize cutting-edge AI models for high-throughput in silico screening to identify novel ciliary cargoes of the intraflagellar transport machinery, followed by experimental validation and mechanistic characterization of promising candidates.

JOB DESCRIPTION

The position leverages AI models for protein structure prediction and artificial protein design to make breakthrough discoveries in cilia biology, a well-established research direction in the laboratory of Professor Esben Lorentzen. The lab is fully equipped with molecular biology and biochemistry facilities, with access to structure determination methods (X-ray crystallography and single-particle cryo-EM) and a GPU computer cluster running AlphaFold, RFdiffusion, BindCRAFT, and other relevant AI models for molecular and structural biology.

WHO WE ARE

The Department of Molecular Biology and Genetics, part of the Faculty of Natural Sciences at Aarhus University, conducts research in Molecular Medicine, Systems Biology, Structural Biology, Plant Molecular Biology, and Quantitative Genetics. The department hosts 220 full-time scientific staff and 140 Ph.D. students.

Please refer the Job description for details