Postdoctoral Research Fellow at Ellison Institute of Technology Oxford Limited
London, East Suffolk - England, United Kingdom -
Full Time


Start Date

Immediate

Expiry Date

09 Feb, 27

Salary

50000.0

Posted On

11 Nov, 26

Experience

3 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

No

Skills

Industry

Healthcare & Life Sciences

Description
  • Bioprocessing & CAR T generation:Processing of patient-derived biomaterials and isolation of specific immune subsets.
  • Primary human T cell culture.
  • Viral and non-viral transduction for generation of CAR T cell populations.


  • Viral transduction:Lentiviral vector production and QC.
  • Design of multi-cistronic lentiviral vector constructs.
  • Optimisation of lentiviral transduction for large construct sizes.


  • Phenotypic and functional assays:Development of characterisation assays for detection of CAR T cells and associated genetic circuitry.
  • Development and optimisation of functional co-culture and real-time imaging assays.
  • Multi-parameter flow cytometry-based readouts.


  • Documentation and communication:Maintenance of detailed experimental records.
  • Analysis and presentation of results internally and with external partners.
  • Prepare internal reports, presentations, protocols, and technical documents.
  • Contribute to management of lab inventory, procurement, and general organisation.
  • Supporting team expansion and management of junior scientist roles.


  • Required Experience/SkillsPhD in immunology/cell therapy.
  • 1+ years post-PhD experience in a relevant industrial or translational academic setting.
  • Extensive experience working with human CAR T cells.
  • Exceptional mammalian cell culture skills using primary immune cells and cell lines, including co-culture and functional assays.
  • Viral transduction experience (lentiviral, retroviral).
  • Strong multi-parameter flow cytometry expertise.
  • Mission-driven, strong attention to detail, and ability to operate independently.
  • Potential and desire to develop scientific leadership skills.


Responsibilities
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