Postdoctoral Scholar at Oregon Health & Science University

Portland, Oregon, United States -

Full Time

Start Date

Immediate

Expiry Date

10 May, 26

Salary

0.0

Posted On

09 Feb, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Cancer Biology, Neurobiology, Neuroimmunology, Sympathetic Nerve Signaling, Tumor Microenvironment, Prostate Cancer, Pancreatic Cancer, Spatial Proteomics, Single-Cell Transcriptomics, Epigenomics, 3D Ex Vivo Models, In Vivo Mouse Models, Mammalian Cell Culture, Imaging Techniques, Cancer-Nerve Interactions, Scientific Curiosity

Industry

Higher Education

Description

Department Overview Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are composed of biologists, chemists, biomedical engineers, computational biologists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy. CEDAR is committed to increasing the diversity of the campus community. We at CEDAR are dedicated to promoting inclusion and multiculturalism to build a successful organization by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires unproven, out-of-the-box thinking. Our research is milestone driven to ensure that each project is fulfilling its stated goals. Every Knight Cancer employee is expected to embody our guiding principles: We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently We SUPPORT each other—Respect leads to trust, which leads to excellence We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone Function/Duties of Position The Eksi Lab at Oregon Health & Science University (OHSU) is seeking a highly motivated and creative postdoctoral fellow with expertise in cancer biology, neurobiology, or neuroimmunology. Our research focuses on how sympathetic nerve signaling remodels the tumor microenvironment to drive cancer progression, with emphasis on prostate and pancreatic cancers. We are particularly interested in the bidirectional communication between tumor-innervating neurons, cancer cells, and immune populations such as mast cells. Our lab integrates spatial proteomics, single-cell transcriptomics, and epigenomics, and advanced 3D ex vivo and in vivo mouse models to dissect neural regulation of cancer. We are specifically seeking candidates with a strong background in ex vivo and in vivo cancer models, including experience in mammalian cell culture, imaging techniques, and a deep interest in uncovering cancer-nerve interactions, whether from a neuroscience or cancer biology perspective. Scientific curiosity and the ability to work across disciplines are essential. Select references: https://link.springer.com/article/10.1007/s10555-025-10241-x https://www.cell.com/iscience/fulltext/S2589-0042(24)01893-5 https://www.nature.com/articles/s41467-021-27615-8 https://www.cell.com/heliyon/fulltext/S2405-8440(24)17240-4 https://www.eu-focus.europeanurology.com/article/S2405-4569(23)00077-9/fulltext https://pubs.rsc.org/en/content/articlelanding/2025/lc/d5lc00134j https://www.biorxiv.org/content/10.1101/2024.12.06.626879v2 (accepted to Cell Reports Methods) Required Qualifications M.D., M.D./Ph.D., or Ph.D. Minimum of 3 years as a graduate student Specialty: Molecular Biology, cell biology, genome sciences, epigenomics, or related field Excellent communication, analytical and organizational skills Ability to work independently and as part of a team while being collaborative in resolving problems Passion for science and inquiry Ability to synthesize one’s own results and others to formulate hypotheses Ability to prioritize multiple tasks at one time Must possess energy and drive to coordinate multiple projects simultaneously Ability to use tact and diplomacy to maintain effective working relationships Preferred Qualifications Ability to synthesize scientific projects and communicate science to diverse audiences Experience with cell culture Experience with microscopy Experience with NGS Experience with data analysis Experience with patient sample processing Oncology experience Additional Details Apply online. Please be sure to upload a Cover Letter and Resume/CV. We offer a variety of benefits on top of joining a thriving organization: Medical, dental and vision coverage at no or low cost to employees Covered 100% for full-time employees and 88% for dependents Several retirement plans to choose from with contributions from OHSU 80 hours of vacation time per year 96 hours of sick leave a year (prorated for part-time employees) Commuter subsidies Tuition reimbursement Access to group life insurance, disability insurance and other supplemental benefits Annual Raises Growth/Development Opportunities Employee discounts to local and major businesses #linkedin #indeed #knightcancerjobs #knightpostdocjobs All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

Responsibilities

The Postdoctoral Scholar will conduct research focusing on how sympathetic nerve signaling remodels the tumor microenvironment to drive cancer progression, particularly in prostate and pancreatic cancers. This involves investigating bidirectional communication between neurons, cancer cells, and immune populations using advanced techniques like spatial proteomics and single-cell transcriptomics.