“RESEARCH FOR A LIFE WITHOUT CANCER” IS OUR MISSION AT THE GERMAN CANCER RESEARCH CENTER. WE INVESTIGATE HOW CANCER DEVELOPS, IDENTIFY CANCER RISK FACTORS AND LOOK FOR NEW CANCER PREVENTION STRATEGIES. WE DEVELOP NEW METHODS WITH WHICH TUMORS CAN BE DIAGNOSED MORE PRECISELY AND CANCER PATIENTS CAN BE TREATED MORE SUCCESSFULLY. EVERY CONTRIBUTION COUNTS – WHETHER IN RESEARCH, ADMINISTRATION OR INFRASTRUCTURE. THIS IS WHAT MAKES OUR DAILY WORK SO MEANINGFUL AND EXCITING.

The Junior Research Group “Translational Radiotheranostics” is seeking for the next possible date a
In the 21st century, cancer will remain one of the leading causes of death worldwide. Our mission is to prevent this through the promising combination of personalized radiodiagnostics and targeted radionuclide therapy – known as radiotheranostics.
The ideal candidate will join the independent Junior Research Group “Translational Radiotheranostics” and is expected to pursue a highly innovative project at the frontiers of interdisciplinary cancer research. The position would start at 50%, with a possible extension to 100% later.

YOUR TASKS

• Development of novel small-molecule and peptide-based radioligands for diagnostic, therapeutic, and theranostic applications; this includes rational drug design based on structure-activity relationships, synthetic route development, and comprehensive chemical and radiochemical characterization
• Radiolabeling of compounds with a broad spectrum of medically relevant radionuclides, including alpha-emitters, beta-emitters, and gamma-emitters
• Optimization of labeling protocols and evaluation of complex stability, radiochemical purity, and shelf-life under physiological conditions
• Functional characterization of radiolabeled compounds using a variety of in vitro assays, including receptor binding, internalization kinetics, and cellular retention studies; these experiments will be conducted independently or in close cooperation with team members
• Integration of feedback from biological testing to guide structural modifications and improve efficacy, specificity, and pharmacological profile
• Preparation of high-quality scientific manuscripts for peer-reviewed journals, as well as writing and contributing to competitive grant proposals and third-party funding applications
• Co-supervision of graduate students, interns, and early-career researchers; support includes training in synthetic chemistry, lab safety, and experimental planning, as well as mentoring on data interpretation, presentation, and scientific communication
• Regular presentation of research results at internal group meetings, institutional seminars, and national and international scientific conferences