THE POSITION

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world here we all have more time with the people we love. That’s what makes us Genentech.

THE OPPORTUNITY

The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated leader who will be supporting small molecule projects in discovery and development.
The DMPK group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

The individual would lead the DMPK strategy, design and execute non-clinical studies in a highly collaborative project team environment. Specifically, the individual will be involved in the following activities as part of their role:

• Representation of DMPK at multi-functional discovery and development project teams
• Lead DMPK strategy as it relates to regulatory setting/interactions; author reports/sections for regulatory briefing packages/filings

• Representation of DMPK at multi-functional discovery and development project teams
• Lead DMPK strategy as it relates to regulatory setting/interactions; author reports/sections for regulatory briefing packages/filing