Protein Engineering Scientist (entry level) at Nabla Bio

Boston, Massachusetts, United States -

Full Time

Start Date

Immediate

Expiry Date

18 Jul, 26

Salary

0.0

Posted On

19 Apr, 26

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Protein engineering, DNA library cloning, Yeast display, MACS, FACS, NGS, Antibody characterization, High-throughput screening, Molecular biology, Assay development, Protein optimization, Laboratory research

Industry

Biotechnology

Description

Nabla Bio is building AI to design new medicines. We combine cutting-edge ML with fast, human-relevant lab validation to create biomolecules on demand. This lets us go after hard diseases and build new drug formats that traditional approaches can’t reach. We’re backed by top investors like Radical and Khosla Ventures and have forged significant partnerships with leading pharma companies. The Role Fueled by partnerships and increasing demand for internal R&D, we will be looking to you to develop and perform high-throughput and multiplex assays for evaluating antibody function. This will include: * Designing and performing high-efficiency DNA library cloning and construction * Implementing high throughput cloning workflows * Executing yeast display selections coupled to MACS/FACS and NGS to characterize libraries of protein and antibody variants * Optimizing therapeutic candidates in lead programs to have desired affinity and developability properties * Working together with our dry-lab and other wet-lab scientists to establish a rapid and seamless production and testing pipeline for characterizing machine learning generated antibody designs Qualifications You are a strong candidate if you have led successful multi-month/year projects featuring direct experience in the above. * Life science-focused MS or BS with 1-2 years research/industry experience are highly desirable. * You must like to work quickly with precision. High aptitude, tenacity, and the foundational knowledge to solve problems outside of your comfort zone is critical. * We will invest heavily in training you, and are committed to helping you grow within Nabla and beyond. What We Offer * A fast-moving environment where you can build and ship tools that impact real drug programs * A small, focused team where your scientific and engineering decisions have outsized impact * Highly competitive salary, equity, and benefits package

Responsibilities

The role involves designing and performing high-throughput assays to evaluate antibody function and optimizing therapeutic candidates. You will collaborate with dry-lab and wet-lab teams to establish a seamless production and testing pipeline for machine learning-generated designs.