Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.
Why? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.
How? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.
PTI’s new approach requires synergy between a diverse team of chemists, machine learning engineers, biologists, and mass spectrometrists. Alzheimer’s disease and aging will be among the first focuses of this technology-driven research organization.

SUMMARY OF POSITION

We are looking for an experienced Mass Spectrometrist who will be working on maintaining MS instruments for running multitudes of samples for a variety of projects in addition to other responsibilities such as advancing and executing hypothesis-driven experiments. In order to be seriously considered for this position, we require a cover letter as part of the candidate’s application.

REQUIRED QUALIFICATIONS

• Masters or PhD in Biology, Biochemistry, or Chemistry.
• 5+ years of experience operating/maintaining mass spectrometers.
• Demonstrated experience optimizing LC-MS/MS methods for bottom-up proteomics.
• Demonstrated mastery of molecular and cellular biology techniques or chemistry techniques.
• Demonstrated enthusiasm and interest in biology and/or analytical chemistry.
• High level of initiative and flexibility, excellent communication and teamwork skills.
• Attention to detail and good time management skills.

PREFERRED QUALIFICATIONS

• Experience with mass spectrometry technological development (hardware or software).
• Proficiency with statistical and computational methods.
• Proficiency with cell culture and sterile technique.

• You will setup, operate, and maintain mass spectrometers from multiple major vendors.
• Analyze experimental data and interpret results for internal and public presentation.
• Designing relevant proteomic experiments.
• Perform protein sample preparation.
• Preparation of lab reagents and media.
• Inventory management and preparation reagents and samples.
• Communication with purchasing and may be responsible for negotiating with various vendors.
• May manage MTAs, software licenses, service contracts, and other documentation.