ABOUT VGXI INC.

VGXI is a leading-edge CDMO dedicated to revolutionizing the biopharmaceutical industry with best-in-class nucleic acid-based products and services. We deliver manufacturing excellence in state-of-the-art facilities with the agility and scale to meet projects of all sizes to serve the global community of next-generation therapeutic developers.
If you are driven by innovation, fueled by scientific curiosity, and committed to making a positive impact on the global pharmaceutical community, you’ve come to the right place. We are always looking for quality-minded, team-oriented individuals who share our dedication to excellence. At VGXI, we’ve cultivated a workplace that people genuinely enjoy being a part of, and we take immense pride in the role they play in shaping our success story. We embrace a culture of quality in our products and in our people. Explore the possibilities, unlock your potential, and contribute to the future of Plasmid DNA manufacturing and precision medicine with VGXI.

SUMMARY

The Quality Control Technician is responsible for in-process and release testing of products manufactured at VGXI. Will provide support for new assay development, method transfers, risk assessments, assay qualifications, change controls and validations. Set-up, organization, and day-to-day operations of a Quality Control Lab are also required.
ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

Responsible for one or more QC assays as follows:

• pH / conductivity
• Osmolality
• Filter Integrity Testing
• DNA Concentration by A260 and Purity by A260/280
• Endotoxin
• Host Cell Protein Quantitation
• Gel electrophoresis
• Restriction
• RNA Quantitation
• Plasmid Forms Analysis
• Transcriptional Activity / Cell Culture
• Host Cell Genomic DNA Quantitation
• Raw Material Release testing
• ELISA assays

EDUCATION AND/OR EXPERIENCE

Bachelor’s or Associate Degree or equivalent from college or technical school; or one to three years related experience and/or training; or equivalent combination of education and experience.

Responsible for one or more QC assays as follows:

• pH / conductivity
• Osmolality
• Filter Integrity Testing
• DNA Concentration by A260 and Purity by A260/280
• Endotoxin
• Host Cell Protein Quantitation
• Gel electrophoresis
• Restriction
• RNA Quantitation
• Plasmid Forms Analysis
• Transcriptional Activity / Cell Culture
• Host Cell Genomic DNA Quantitation
• Raw Material Release testing
• ELISA assay

Responsible for documentation/administration as follows:

• Organize all accumulated data.
• Keep notebooks up to date, signed, and reviewed.
• Write reports as needed and enter data in software programs.
• Write Standard Operating Procedures and Protocols

Responsible for QC analysis as follows:

• Spectramax software
• HPLC software
• Gel imaging software
• PowerPoint, Excel and Word softwar

Other General Duties:

• Lab supplies (stocked, ordered and labeled)
• Cleaning lab (trash removal, sweeping, etc.)
• Cleaning glassware (washing, autoclaving)
• Calibration and preventive maintenance of equipmen