Research Associate - Advance characterization at Dr Reddy's Laboratories Limited

Bachupalle, Andhra Pradesh, India -

Full Time

Start Date

Immediate

Expiry Date

25 May, 26

Salary

0.0

Posted On

24 Feb, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

LCMS, Protein Characterization, LC-MS/MS, QTOF, MALDI TOF, 2D LC QTOF, IM QTOF, Biosimilars Characterization, Intact Mass Analysis, Subunit Mass, Peptide Mapping, PTM Analysis, Method Development, Qualification, ADC's Characterization, HCP Workflows

Industry

Pharmaceutical Manufacturing

Description

Company Description Dr. Reddy’s Laboratories Ltd. is a leading multinational pharmaceutical company based across global locations. Each of our 24,000 plus employees comes to work every day for one collective purpose: to accelerate access to affordable and innovative medicines because Good Health Can’t Wait. We started in 1984 with a modest investment, 20 employees and a bold vision. Today, we have research and development centres, manufacturing facilities or a commercial presence in 66 countries. For nearly four decades, we have stood for access, affordability and innovation based on the bedrock of deep science, progressive people practices and robust corporate governance. As the pharmaceutical industry evolves and undergoes disruption, we see an opportunity – to strengthen our core further (the next steps) and to build the future (the new bets). ‘The Next and the New’ is how we aim to continue to be the partner of choice – purpose-driven, future-ready and sustainable. Our aim is to reach over 1.5 Bn+ patients across the world by 2030 by growing our core businesses and building for the future with sustainability at the core of our purpose and strategy. Sustainability for us means operating in a manner that respects people, planet and purpose – helping us conserve precious resources, serve our patients, create value for stakeholders, give back to society, fulfil our potential and maintain our integrity and transparency Dr Reddy’s maintains a work environment, free from discrimination and is an equal opportunity employer. We are committed to employ & nurture all qualified diverse workforce without regard to race, colour religion, nationality, sex, age, disability status, genetics, sexual orientation, gender expression, citizenship or any other characteristic or classification protected by applicable law(s) of the country we operate in. We treasure every talent, and recognize merit and diversity in our organization. " Job Description Job Summary We are looking for an experienced professional to design and execute LCMS experiments for protein characterization. The primary objective is to develop a robust methods using LCMS for CAA/Bio-similarity, contributing to the advancement and success of the team's objectives within the product development domain. Roles & Responsibilities Deep understanding on protein/mAbs characterization using LC-MS/MS (QTOF, MALDI TOF, 2D LC QTOF, IM QTOF etc.). Complete, in-dept knowledge on Biosimilars characterization (Intact mass analysis, subunit mass, peptide mapping, PTM analysis, etc.) using LC-MS/MS. Experience on mAbs bio similarity, CAA using LCMS. Experience on method development and qualification for various mAb’s using LC-MS/MS. Knowledge on ADC’s characterization Knowledge on HCP and MAM workflows is preferred. Preferred knowledge on Targeted proteomics/Protein quantitation, Impurities analysis and spent media analysis using TQLCMS Characterization of SSR/Signal peptides Understanding on good laboratory practices and Good Documentation Practices. The candidate should have good knowledge and skills to independently plan and execute method development and validation activities for the functional characterization. To take up new technology initiatives within the development group and to draft primary documents. Interpret data, draw conclusions, and present data results at group meetings and other forums. Prepare protocol / report / manuscript as needed, including contributions to writing and reviewing content. Collaborate with cross-functional teams to support development projects. Ensuring compliance with Good Documentation Practices (GDP). Ensure safe practices in the facilities and participate in the organization-based safety and quality initiatives. Qualifications Educational Qualification A Master’s degree (M.Sc. or M.Tech. or or M.Pharm.) or Ph.D. in Proteomics, Biotechnology, Biochemistry. Minimum Work Experience Master degree with minimum 2-5 years or PhD with 0-1 years of working experience on Method development, qualification, Handling of analytical instruments like HRMS, TQ LCMS, Synapt, Xevo QTOF, 2D LC QTOF etc. Skills & Attributes Technical Skills An understanding of the analytical Development for Biotherapeutics/ Biosimilars. In-depth knowledge LCMS QTOF. Deep understanding of analytical techniques, statistical analysis, data management and analysis. Behavioral Skills Possesses team-building capability, fostering positive collaboration and cohesion. Good verbal and written communication skills, facilitating effective interaction. A strong learning ability, quickly acquiring new knowledge and skills. Is self-motivated, taking initiative and showing enthusiasm for tasks and responsibilities. Exhibits troubleshooting skills, effectively identifying and resolving issues. Good interpersonal skills, fostering positive relationships and effective communication. Additional Information About the Department - Global Manufacturing Organisation (GMO) At Dr. Reddy's Laboratories, we are dedicated to making a meaningful impact on global healthcare through precision manufacturing and innovation. With a legacy of excellence, we are a leading force in the pharmaceutical industry. We operate 19 state-of-the-art manufacturing plants across Hyderabad, Vizag, Baddi, Mexico, Shreveport, and Mirfield, comprising 8 OSD facilities, 3 Injectables facilities, and 8 API facilities. Benchmarking manufacturing processes and continuous operational excellence are at the core of our capability to deliver quality medicines to our patients in 66 countries. We manufacture a portfolio of complex APIs and 1,150+ drug master files across key therapy areas such as Oncology, Cardio-vascular, Central Nervous System and Anti-Diabetes. The World Economic Forum has recognised our largest manufacturing facility in Bachupally, Hyderabad, as part of its Global Lighthouse Network. We aspire to be the most efficient pharma operations in the world. Our productivity improvement and digitalisation efforts are key to staying competitive, meeting business imperatives, and meeting our ambitious ESG goals. Building such ‘factories of the future’ is integral to innovation and to build healthcare of the future. " Benefits Offered At Dr. Reddy’s we actively help to catalyse your career growth and professional development through personalised learning programs. The benefits you will enjoy at Dr. Reddy’s are on par with the best industry standards. They include, among other things and other essential equipment, joining & relocation support, family support (Maternity & Paternity benefits), learning and development opportunities, medical coverage for yourself and your family, life coverage for yourself. " Our Work Culture Ask any employee at Dr. Reddy’s why they come to work every day and they’ll say, because Good Health Can’t Wait. This is our credo as well as the guiding principle behind all our actions. We see healthcare solutions not only as scientific formulations, but as a means to help patients lead healthier lives, and we’re always attuned to the new and the next to empower people to stay fit. And to do this, we foster a culture of empathy and dynamism. People are at the core of our journey over the last few decades. They have been supported by an enabling environment that buoys individual ability while fostering teamwork and shared success. We believe that when people with diverse skills are bound together by a common purpose and value system, they can make magic. For more details, please visit our career website at https://careers.drreddys.com/#!/ " Job Family: Research & Development Sub Job Family: Advanced Characterisation Technique Business unit: Biologics

Responsibilities

The primary objective is to design and execute LCMS experiments for protein characterization, focusing on developing robust methods for CAA/Bio-similarity to support product development goals. Responsibilities include deep understanding and application of various LC-MS/MS techniques for complex protein analysis and contributing to new technology initiatives.