Research Associate I-II, Conjugation Chemistry at ADARx Pharmaceuticals Inc.

San Diego, California, United States -

Full Time

Start Date

Immediate

Expiry Date

10 Jun, 26

Salary

75000.0

Posted On

12 Mar, 26

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Organic Synthesis, Analytical Chemistry, Oligonucleotide Conjugates, RP-HPLC, LC-MS, Experimental Design, Protocol Development, Problem Solving, Laboratory Operations, Hazardous Material Management, Communication, Organizational Skills, Microsoft Office Suite, Adaptability, Self-Motivation

Industry

Biotechnology Research

Description

We are seeking a highly motivated and qualified individual to join our Discovery Chemistry Department as a Research Associate and work as part of a team to drive success. The successful candidate will support ongoing RNA-based drug discovery projects in several therapeutic areas. This role will be expected to be an active participant and participate in experimental design and planning. Essential Responsibilities: * Develop and promote a workplace culture that values diversity of thought, promotes integrity and creates an atmosphere that supports coaching and fosters accountability. * Carry out assigned laboratory functions applying knowledge and skill in an accurate, timely manner. * Establish and maintain excellent working relationships with critical collaborative partners throughout the company. * Synthesis, characterization, and purification of novel oligonucleotide conjugates * Identify critical issues/steps in conjugation and solve problems in a timely fashion. * Development and optimization of conjugation protocols using novel chemistries and techniques. * Track progress against project timelines, generate regular status updates, and communicate progress and issues to management. * Manage and maintain equipment, reagents and dedicated laboratory environment needed to carry out assignments; Troubleshoot and solve equipment/technical problems. * Maintain updated and well-organized lab notebooks. * Execute daily laboratory operations with an approach designed to minimize risks and hazard waste streams. * Maintain all appropriate corporate standards for facility safety and hazardous material management. * Other duties as assigned. Essential Physical Characteristics: Reasonable accommodation(s) may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case-by-case basis. On-Site Protocol: Physical presence at the ADARx Pharmaceuticals worksite is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture. Qualifications: * BS or MS in Chemistry or a related discipline with excellent understanding of organic and analytical chemistry. * Previous experience working in an organic synthesis, chemistry or analytical laboratory is preferred. * Good working knowledge with a wide range of analytical techniques, especially RP-HPLC and LC-MS. * Excellent analytical, communication, and organizational skills. * Proficiency working with Microsoft Office Suite Products. Preferred Qualifications: * Prior experience in biotech/pharmaceutical industry a plus. * Previous experience with RNA/oligonucleotide therapeutics is preferred but not essential. Required Key Attributes: * Must be able to work independently with supervision as needed. * Proficient at working independently as well as in cross-functional team settings * Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism. * Self-motivated with excellent interpersonal, organizational and communication skills with the ability to take a hands-on approach to work effectively in a dynamic and collaborative, fast-paced environment. * Strong problem-solving skills and a proactive attitude towards exploring new approaches. Compensation: * This is a full-time position, Monday-Friday. * Pay is commensurate with experience. * Equity-based compensation * Performance-based bonuses * 401(k) with Company Match * Medical, Dental, Vision * Flexible Spending Account * Life Insurance * Employee Assistance Program * Employee Discounts * Gym Membership * Paid Vacation * Paid Holidays * Paid Sick, Jury Duty, Bereavement Work Authorization: * United States (Required) * Background Check * As a condition of employment, you must successfully complete all post-offer, pre-employment requirements, including but not limited to a background check. Company Overview: ADARx Pharmaceuticals, Inc., (the “Company” or “ADARx”) located in San Diego, is a clinical stage biotechnology company dedicated to transforming cutting-edge science into next-generation RNA therapeutics to treat a broad spectrum of diseases. Our goal is to control the expression of specific disease drivers with highly selective RNA targeted therapies, delivering life-changing treatments for patients with urgent unmet medical needs. ADARx Pharmaceuticals is an EEO employer committed to an exciting, diverse, and enriching work environment. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. Disclosure Statement: * The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. * Data: Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. * Recruiters & Staff Agencies: ADARx Pharmaceuticals (ADARx) does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to ADARx or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of ADARx and the Company will not owe any referral or other fees with respect thereto. * Compensation: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual target bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, type and length of experience within the industry, and other job-related factors permitted by law. * Total Compensation: Includes base salary; benefits: medical, vision, and dental insurance; life insurance; 401(k) matching program; paid time off; paid holidays; Employee Assistance Program; and other employee benefits. This role may also be eligible for short-term or long-term incentive compensation, including but not limited to cash bonuses. * Conditional Offer of Employment: Following a conditional offer of employment, satisfactory completion of a background check (including criminal records check) is required prior to beginning employment. Any offer of employment may be rescinded if the background check reveals disqualifying information, and/or it is discovered that the candidate knowingly withheld or falsified information. Failure to satisfactorily complete the background check may affect the continued employment of a current NAI employee who was conditionally offered the position.

Responsibilities

The role involves the synthesis, characterization, and purification of novel oligonucleotide conjugates while developing and optimizing conjugation protocols using new chemistries and techniques. Essential duties also include maintaining laboratory standards, tracking project progress, and communicating updates to management.