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ABOUT THE ROLE

The Brancaccio Lab invites applications from talented, highly motivated and creative postdoctoral scientists to take a leading role in one of the following projects investigating molecular cellular and circuit mechanisms driving circadian dysfunction in pre-clinical models of Alzheimer’s disease (AD).
Today, over 1 million people in the UK are living with dementia and related neurodegenerative disorders, such as Alzheimer’s, Parkinson’s, and motor neuron disease (MND). The impact of these incurable and progressive conditions on individuals and their families is devastating. The cost to the economy and public services is large and growing as the UK population ages. However, due to major advances in our understanding of the biology of these diseases, the scientific field is at a tipping point, with the next decade promising to deliver transformative breakthroughs in therapies and a new era of predictive, preventative, and precision medicine for neurodegenerative conditions. The UK is well placed to play a leading role in this revolution due to its scientific strengths in the field, led by the UK Dementia Research Institute (UK DRI) working with our world-class, university-based centres. We are a globally leading multidisciplinary research institute of over 900 staff investigating the spectrum of neurodegenerative disorders causing dementia, driving a step change in our understanding of neurodegeneration, and accelerating the discovery, development and delivery of interventions that will help diagnose, treat, and ultimately prevent dementia. Our principal funder is the Medical Research Council (MRC).

This role is part of the UK Dementia Research Institute at Imperial College London, located in the Department of Brain Sciences. You will benefit from an active research (and social) environment in the Department of Brain Sciences, with additional research labs in the Sir Michael Uren Hub on the nearby White City Campus. Postdocs in the UK DRI at Imperial enjoy excellent career development opportunities with:

• Access to a range of cutting-edge technologies, i.e., real-time live imaging for circadian gene expression and neuronal and glial metabolic function, automated behavioural testing, single cell/nuclei transcriptomics, Imaging Mass Cytometry and computational modelling.
• An inclusive and collegial working environment.
• Strong national links through the UK DRI with attendance at its annual scientific meeting ‘Connectome’.
• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
• Grow your career: Gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression
• Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes)