Research Fellow (Cell Biology/Biophysics/Bioengineering/Biochemistry) at Nanyang Technological University Singapore

Singapore, , Singapore -

Full Time

Start Date

Immediate

Expiry Date

17 May, 26

Salary

0.0

Posted On

16 Feb, 26

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Biophysics, Cell Biology, Bioengineering, Biochemistry, Biomolecular Condensates, Phase Separation, Genetic Engineering, Cloning Techniques, CRISPR/Cas9, Optogenetic Tool Development, Quantitative Imaging, Live-Cell Confocal Microscopy, Super-Resolution Microscopy, Automated Image Analysis, Generative Models, Protein Design

Industry

Education Administration Programs

Description

The Institute for Digital Molecular Analytics and Science (IDMxS), officially launched on 1 December 2022, is a Research Centre of Excellence (RCE) supported by a total investment of around S$160 million over 10 year. IDMxS’ overarching approach is to go beyond the neat simplicity of intermolecular interactions in dilute media and embrace the inherent complexity of biological interactions and dense heterogeneity of their environments. For more details, please view www.bussilab.com and https://idmxs.org/research-theme-2/ We are looking for a highly motivated and creative Postdoc Research Fellow to join our team and lead an exciting project investigating the functional interactions between biomolecular condensates and membrane-bound organelles in different cellular models. This project aims to bridge the gap between membrane-less and membrane-bound compartments, deciphering how phase separation influences organelle dynamics, signaling, and function. Key Responsibilities: Research Leadership: Spearhead an independent project decoding the functional crosstalk between condensates and membrane-bound organelles. Tool Engineering: Design and validate novel molecular probes or synthetic condensates, leveraging genetic engineering or generative protein design. Quantitative Imaging: Apply advanced microscopy and image analysis pipelines to measure biophysical dynamics in living cells. Output & Mentorship: Drive the publication of high-impact findings and assist in the supervision of junior lab members. Requirements: We are looking for a candidate who is eager to work at the intersection of biophysics and cell biology. PhD in Cell Biology, Biophysics, Bioengineering, Biochemistry, or a related field Core Expertise: Strong background in the biophysics of biomolecular condensates (phase separation) and fundamental cell biology. Genetic Engineering: Advanced cloning techniques, CRISPR/Cas9 editing, or optogenetic tool development. Quantitative Imaging: Live-cell confocal and/or super-resolution microscopy, or automated image analysis pipelines. Computational Protein Design: Experience with generative models (e.g., AlphaFold, RFdiffusion, ProteinMPNN) for designing novel condensate drivers or sensors. Collaborative and interdisciplinary research environment. Access to state-of-the-art imaging and biophysical instrumentation. Mentorship committed to your career development and independence. We regret to inform that only shortlisted candidates will be notified. Hiring Institution: NTU A research-intensive public university, Nanyang Technological University, Singapore (NTU Singapore) has 33,000 undergraduate and postgraduate students in the Engineering, Business, Science, Humanities, Arts, & Social Sciences, and Graduate colleges. It also has a medical school, the Lee Kong Chian School of Medicine, established jointly with Imperial College London. NTU is also home to world-class autonomous institutes – the National Institute of Education, S Rajaratnam School of International Studies, Earth Observatory of Singapore, and Singapore Centre for Environmental Life Sciences Engineering – and various leading research centres such as the Nanyang Environment & Water Research Institute (NEWRI) and Energy Research Institute @ NTU (ERI@N). Ranked amongst the world’s top universities by QS, NTU has also been named the world’s top young university for the past seven years. The University’s main campus is frequently listed among the Top 15 most beautiful university campuses in the world and has 57 Green Mark-certified (equivalent to LEED-certified) buildings, of which 95% are certified Green Mark Platinum. Apart from its main campus, NTU also has a campus in Novena, Singapore’s healthcare district. Under the NTU Smart Campus vision, the University harnesses the power of digital technology and tech-enabled solutions to support better learning and living experiences, the discovery of new knowledge, and the sustainability of resources. For more information, visit www.ntu.edu.sg About NIE About RSIS About LKCMedicine About NTUItive

Responsibilities

The Research Fellow will spearhead an independent project focused on decoding the functional crosstalk between biomolecular condensates and membrane-bound organelles, while also designing and validating novel molecular probes or synthetic condensates.