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Research Fellow-Precision Medicine at Mayo Career Site US

Rochester, Minnesota, United States -

Full Time

Start Date

Immediate

Expiry Date

16 Mar, 26

Salary

0.0

Posted On

16 Dec, 25

Experience

2 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Molecular Biology, Cell Culture, DNA Studies, RNA Studies, Protein Studies, Gene Editing, Flow Cytometry, Mouse Work, Xenograft Model

Industry

Hospitals and Health Care

Description

We are seeking exceptional post-doctoral research fellows/scientists to work in the field of precision medicine. The Shah lab at Mayo Clinic focuses on the development of and treatment for an aggressive blood cancer known as TP53-mutated myeloid neoplasm. These leukemias are highly aggressive and have no effective therapies yet. Two general themes in lab include (i) Pathogenesis of TP53mut MN and (ii) Drug discovery. The applicant will focus mainly on the pathogenesis projects. Specifically, we are interested in understanding the sequence of events that leads to the development of the leukemia. Studying these events can hopefully allow to intervene before the leukemia develops. We employ in vitro (using patient samples) and in vivo studies to that end. Successful candidate will have a PhD in molecular biology or related fields with 1-3 years of experience and a strong publication record. Candidates should be well versed in standard cellular and molecular biology techniques (cell culture, DNA, RNA, and protein studies, gene editing, and flow cytometry). Interest and prior experience with mouse work—including xenograft model—is highly desired.

Responsibilities

The applicant will focus on understanding the pathogenesis of TP53-mutated myeloid neoplasm. This involves studying the sequence of events leading to leukemia development using in vitro and in vivo methods.