DESCRIPTION

Develop advanced and robust LC-MS analytical methods for the bioanalysis of different molecular formats such as small molecules, oligonucleotides, peptides, and/or proteins. Develop and implement innovative high-resolution mass spectrometry-based metabolite profiling and identification platforms Perform LC-MS-based small molecule biomarker analysis occasionally Review and translate complex LC-MS-based data sets and articulate findings to project teams Maintain/document records of all experiments, including QC review data, experimental results, and reports as appropriate into electronic laboratory notebooks Contribute to the team’s knowledge through updating scientific literature and discussions Maintain and troubleshoot lab instruments such as biological sample extraction systems, HPLC, and LC-MS

SKILLS

lc-ms, mass spectrometry, gmp, Method development, oligonucleotide

TOP SKILLS DETAILS

lc-ms,mass spectrometry,gmp,Method development,oligonucleotide

ADDITIONAL SKILLS & QUALIFICATIONS

1. PhD or Master’s degree in pharmaceutical sciences, analytical chemistry, chemistry or related disciplines with relevant bioanalysis experience from industry or academia required. (Fellowship work can be counted as relevant experience, but preference will be given to a scientist with CRO bioanalysis experience) 1. Strong LC-MS bioanalysis experience with method development and troubleshooting. 2. Hands-on with at least one MS (Mass Spec) platform (e.g., Sciex 6500/7500, Thermo QE-HF, Q-Exactive, Q-TOF 4800). 3. PhD with 3–5 years of experience (senior candidates welcome for Level III). 4. Experience in oligonucleotide research and bioanalysis. 5. Strong LC-MS skills required; ADME/PKPD experience is a plus. 6. Willing to commit to a 12–14 month contract (potential for FTE conversion). 7. Open to relocation at own expense if able to meet the start date. 8. Prioritize method development experience over routine sample analysis. 9. Familiarity with Analyst (Sciex), Xcalibur (Thermo), or similar software. 10. Background in CRO, pharma, biotech, with diverse modalities. 11. Clear communicator with a long-term contributor mindset.

EXPERIENCE LEVEL

Intermediate Level

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave