Research Specialist- School of Medicine, Hematology at Emory University

Atlanta, Georgia, United States -

Full Time

Start Date

Immediate

Expiry Date

15 Jun, 26

Salary

0.0

Posted On

17 Mar, 26

Experience

0 year(s) or above

Remote Job

Yes

Telecommute

Yes

Sponsor Visa

Skills

Bioinformatics, RNA Sequencing, ATAC-seq, DNA Sequencing, Proteomics, Metabolomics, Gene Expression Analysis, Pathway Enrichment Analysis, Network Analysis, Clonal Evolution, Lineage Tracing, Functional Genomics, CRISPR Screens, Machine Learning, Predictive Algorithms, R

Industry

Higher Education

Description

Discover Your Career at Emory University Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the excellence of our academic community. Description The Bhatt Laboratory in the Department of Hematology and Medical Oncology at Emory University School of Medicine is seeking a highly motivated Bioinformatician to join our dynamic research team. The successful candidate will work on high-impact translational research projects that bridge computational analysis with functional biology to identify novel therapeutic strategies for patients with blood cancers. The lab has established a strong track record of high-impact publications and has received prestigious funding from organizations including the American Cancer Society, European Molecular Biology Organization, American Association for Cancer Research, American Society of Hematology, and The Leukemia & Lymphoma Society. Lab website: https://www.bhatt-lab.com KEY RESPONSIBILITIES: Under general supervision, performs a variety of defined research and laboratory tests and experiments according to prescribed protocols and assigned schedules. Sets up experiments as prescribed by a principal investigator. May be required to participate in laboratory maintenance activities such as sterilization and cleaning of equipment, ordering of supplies, inventory and media preparation. Maintains records, files and logs of work performed in laboratory notebooks and computer databases. Compiles data and records results of studies for publications, grants and seminar presentations. Employees in this classification may be required to work with, take specific precautions against and/or be immunized against potentially hazardous agents. Performs related responsibilities as required by principal investigator. ADDITIONAL RESPONSIBILITIES: Analyze large-scale multi-omics datasets including bulk and single-cell RNA sequencing, ATAC-seq, DNA sequencing, proteomics, and metabolomics data from AML patient samples and preclinical models Perform differential gene expression analysis, pathway enrichment analysis, and network analysis to identify key regulators of therapy resistance Analyze clonal evolution and lineage tracing data to map resistance trajectories during AML treatment Integrate functional genomics data (CRISPR screens) with transcriptomic and epigenomic datasets to identify therapeutic vulnerabilities Develop machine learning models to predict therapeutic response based on multi-omics features Build predictive algorithms for patient stratification using dynamic BH3 profiling data and molecular profiles Apply dimensionality reduction techniques and clustering methods to identify AML subpopulations with distinct resistance mechanismsEducation and Experience MINIMUM QUALIFICATIONS: Bachelor's degree in a scientific field OR equivalent combination of experience, education, and training. PREFERRED QUALIFICATIONS: Bachelor's degree in Bioinformatics, Computational Biology, Data Science, Computer Science, Statistics, or related field with experience in bioinformatics analysis of genomics data (RNA-seq, scRNA-seq, ATAC-seq, or similar)Technical Skills Strong programming skills in R and/or Python, Experience with next-generation sequencing data analysis tools and pipelines, Proficiency in statistical analysis and data visualization, Familiarity with high-performance computing environments and cluster job submission systems, Experience with version control systems (Git/GitHub) Additional Details Emory is an equal opportunity employer, and qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by state or federal law. Emory University does not discriminate in admissions, educational programs, or employment, including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Students, faculty, and staff are assured of participation in university programs and in the use of facilities without such discrimination. Emory University complies with Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity, and affirmative action (for protected veterans and individuals with disabilities). Inquiries regarding this policy should be directed to the Emory University Department of Equity and Civil Rights Compliance, 201 Dowman Drive, Administration Building, Atlanta, GA 30322. Telephone: 404-727-9867 (V) | 404-712-2049 (TDD). Emory University is committed to ensuring equal access and providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to seek a reasonable accommodation, please contact the Department of Accessibility Services at accessibility@emory.edu or call 404-727-9877 (Voice) | 404-712-2049 (TDD). We kindly ask that requests be made at least seven business days in advance to allow adequate time for coordination.

Responsibilities

The role involves performing defined research tests and experiments under supervision, setting up prescribed experiments, and maintaining laboratory records and logs. Key duties also include compiling data and results for presentations and publications.